snx12
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  • Official Full Name
  • sorting nexin 12
  • Background
  • This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a protein of unknown function.
  • Synonyms
  • SNX12; sorting nexin 12; sorting nexin-12; 2610001F05Rik; AW045757; MGC118982; MGC118983; RGD1565585; RP23-356J7.1; SDP8; SNX 12; SNX12_HUMAN; OTTHUMP00000023487; OTTHUMP00000023488
Cat.#:SNX12-4389RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SNX12 Protein, His-tagged
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Cat.#:SNX12-3177CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SNX12
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Cat.#:SNX12-11345ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SNX12
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Cat.#:SNX12-7395ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SNX12
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Cat.#:SNX12-7396ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SNX12
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Cat.#:SNX12-7397ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SNX12
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Cat.#:SNX12-1601HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SNX12 293 Cell Lysate
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Involved Pathway

SNX12 involved in several pathways and played different roles in them. We selected most pathways SNX12 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX12 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endocytosis
ASAP1; ASAP2B; ARPC4; SH3GLB1; CAPZA1; PIP5K1AA; DNM2A; CHMP4C; SH3GL2; CHMP2B

Protein Function

SNX12 has several biochemical functions, for example, enzyme binding, phosphatidylinositol binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX12 itself. We selected most functions SNX12 had, and list some proteins which have the same functions with SNX12. You can find most of the proteins on our site.
Function
Related Protein
Function enzyme binding
Related Protein CTNNBL1; ANK1; TNKS2; RAD9; LAMB1; PARK7; HAND2; UGT1A2; SLPI; ATF7
Function phosphatidylinositol binding
Related Protein SNX17; ITPR2; SNX8; NISCH; SH3PXD2A; PLD2; SNX16; TNFAIP8L3; SNX2; GRB7
Function protein binding
Related Protein RGS7BP; NEK3; JAM2; MIEN1; MX1; ENC1; KRT15; UBE2N; ARMC1; BCS1L

Interacting Protein

SNX12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX12.
ARL6IP1; ABL1; FYN; NCK1; GRB2; pi3p; CDC5L

SNX12 Related Articles

Wang, X; Huang, T; et al. Dysregulation of protein trafficking in neurodegeneration. MOLECULAR NEURODEGENERATION 9:-(2014).
Angel, JM; Abel, EL; et al. Fine Mapping Reveals That Promotion Susceptibility Locus 1 (Psl1) Is a Compound Locus With Multiple Genes That Modify Susceptibility to Skin Tumor Development. G3-GENES GENOMES GENETICS 4:1071-1079(2014).