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Official Full Name Sp3 transcription factor
Background The sequence-specific transcription factor Sp3 binds GC and GT box sequences in the promoters of a variety of genes. The Sp3 transcription factor contains three zinc finger domains that determine sequence specificity of DNA binding. This transcription fac
Synonyms SP3; Sp3 transcription factor; transcription factor Sp3; SPR 2; specificity protein 3; GC-binding transcription factor Sp3; SPR2; DKFZp686O1631
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • SL2
    • Wheat Germ
    • Tag :
    • Flag
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SP3-5127H Recombinant Human SP3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Sp3-6061M Recombinant Mouse Sp3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human SP3-104H Recombinant Human SP3, MYC/DDK-tagged HEK293 Myc/DDK
    Human SP3-2094H Recombinant Human Sp3 Transcription Factor, FLAG-tagged SL2 Flag
    Human SP3-31436TH Recombinant Human SP3 Wheat Germ N/A
    Human SP3-903H Recombinant Human SP3 protein, GST-tagged Wheat Germ GST
    Mouse SP3-15794M Recombinant Mouse SP3 Protein Mammalian Cell His
    Chicken SP3-6171C Recombinant Chicken SP3 Mammalian Cell His

    SP3 involved in several pathways and played different roles in them. We selected most pathways SP3 participated on our site, such as Regulation of Telomerase, SIDS Susceptibility Pathways, Selenium Metabolism and Selenoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with SP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Regulation of Telomerase SP3; NR2F2; CMTM2A; TNKS; MXD1; PINX1; DKC1
    SIDS Susceptibility Pathways LMX1B; SCN3B; EN1; POU3F2; TSPYL1; PHOX2A; KCNH2; YBX1; TPH2; KCNJ8
    Selenium Metabolism and Selenoproteins TXNRD3IT1; CREM; SELT; TRNAU1AP; MSRB1; TXNRD2; SP3; SELENBP1; FBXO17; SELK

    SP3 has several biochemical functions, for example, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SP3 itself. We selected most functions SP3 had, and list some proteins which have the same functions with SP3. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II core promoter sequence-specific DNA binding RREB1; ZFPM1; GATA1; SP1; MTF1; TAL1; RBPJ; STAT6; H3F3A; RUNX2
    RNA polymerase II regulatory region sequence-specific DNA binding ZNF691; SATB1; ZNF584; MYOD1; ATF4B2; H2AFY; ARID3A; PRKCBP1L; NR1I2; PLAGL1
    RNA polymerase II transcription factor activity, sequence-specific DNA binding CC2D1A; FOXO3A; ATF4B2; FOXG1C; TFDP1A; ETV5B; MED1; RUNX3; FOXJ1; ERG
    chromatin binding PDX1; JUN; MCM5; KAT2B; MED12; JMJD5; NEUROG1; PHF21B; SMC1A; PRMT6
    core promoter proximal region sequence-specific DNA binding DMRT3; KLF4; DMRTA1; DMRT1; DMRTC1C2; SMAD4; GATA3; DMRTC2; PAX2; DMRTC1B
    metal ion binding KLF11A; KLF7A; BTY; ZFPM2A; GNAI2; ZNF317; CHPF; RPAIN; SP2; CYP26C1
    protein binding RABEP1; MYL12A; ZNF143; CEP152; LTC4S; AGT; ANKS4B; H3F3A; TRIM74; ITPKB
    transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding HES1; ZFP90; BTG2; SREBF2; KLF17; NFIL3-4; POU4F2; RCOR1; GFI1; ESRRA

    SP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SP3.

    ESR1; GABPA; gc_box_foxp3_promoter_probe; prkra_human_gene; GCH1; HTT; STK19; q5nig6_fratt; dnaC_26; yfkA; mdm2_human_probe; bmf_human_gene

    Mizukami, M; Tokunaga, H; et al. Highly efficient production of VHH antibody fragments in Brevibacillus choshinensis expression system. PROTEIN EXPRESSION AND PURIFICATION 105:23-32(2015).
    Yang, Y; Deng, Y; et al. The Amino Acids 736-761 of the MERS-CoV Spike Protein Induce Neutralizing Antibodies: Implications for the Development of Vaccines and Antiviral Agents. VIRAL IMMUNOLOGY 27:543-550(2014).

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