spire2
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  • Official Full Name
  • spire homolog 2 (Drosophila)
  • Synonyms
  • SPIRE2; spire homolog 2 (Drosophila); protein spire homolog 2; KIAA1832; spir 2; MGC117166; Spir-2; SPIR2_HUMAN
Cat.#:SPIRE2-2923HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SPIRE2, His-tagged
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Cat.#:SPIRE2-15903MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SPIRE2 Protein
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Cat.#:SPIRE2-1731ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SPIRE2
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Cat.#:SPIRE2-1506HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SPIRE2 293 Cell Lysate
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Involved Pathway

SPIRE2 involved in several pathways and played different roles in them. We selected most pathways SPIRE2 participated on our site, such as Dorso-ventral axis formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPIRE2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Dorso-ventral axis formation
PIWIL1; NOTCH1; MAP2K1; MAPK3; CPEB1B; CPEB2; ETS1; SPIRE2; FMN2; GRB2

Protein Function

SPIRE2 has several biochemical functions, for example, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPIRE2 itself. We selected most functions SPIRE2 had, and list some proteins which have the same functions with SPIRE2. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein IPP; MKL1; CAPZA2; ACTN4; FSCN1; MSRB1A; WHAMM; ENC1; SCIN; EPB41L1

Interacting Protein

SPIRE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPIRE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPIRE2.
Fbxw11

SPIRE2 Related Articles

Pechlivanis, M; Samol, A; et al. Identification of a Short Spir Interaction Sequence at the C-terminal End of Formin Subgroup Proteins. JOURNAL OF BIOLOGICAL CHEMISTRY 284:25324-25333(2009).
Quinlan, ME; Hilgert, S; et al. Regulatory interactions between two actin nucleators, Spire and Cappuccino. JOURNAL OF CELL BIOLOGY 179:117-128(2007).
Schumacher, N; Borawski, JM; et al. Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain. GENE EXPRESSION PATTERNS 4:249-255(2004).
CHEUNG, HK; SERANO, TL; et al. EVIDENCE FOR A HIGHLY SELECTIVE RNA TRANSPORT-SYSTEM AND ITS ROLE IN ESTABLISHING THE DORSOVENTRAL AXIS OF THE DROSOPHILA EGG. DEVELOPMENT 114:653-661(1992).