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SPIRE2

Official Full Name

spire homolog 2 (Drosophila)
Synonyms

SPIRE2; spire homolog 2 (Drosophila); protein spire homolog 2; KIAA1832; spir 2; MGC117166; Spir-2; SPIR2_HUMAN;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SPIRE2-2923H	Recombinant Human SPIRE2, His-tagged	E.coli	His	318-666aa	$319 / 25ug
Human	SPIRE2-1506HCL	Recombinant Human SPIRE2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SPIRE2-4646H	Recombinant Human SPIRE2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	SPIRE2-15903M	Recombinant Mouse SPIRE2 Protein	Mammalian Cell	His		Inquiry
Mouse	SPIRE2-8661M	Recombinant Mouse SPIRE2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Spire2-6101M	Recombinant Mouse Spire2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	SPIRE2-8661M-B	Recombinant Mouse SPIRE2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	SPIRE2-1731Z	Recombinant Zebrafish SPIRE2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SPIRE2 Related Articles

SPIRE2 involved in several pathways and played different roles in them. We selected most pathways SPIRE2 participated on our site, such as Dorso-ventral axis formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPIRE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Dorso-ventral axis formation	PIWIL4;NOTCH2;PIWIL2;MAPK1;CPEB2;SPIRE1;CPEB1B;KRAS;EGFRA

SPIRE2 has several biochemical functions, for example, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPIRE2 itself. We selected most functions SPIRE2 had, and list some proteins which have the same functions with SPIRE2. You can find most of the proteins on our site.

Function	Related Protein
actin binding	MYO10;PHACTR3B;KIF18A;SCINLA;INPPL1B;DMD;NRAP;SSH2;PLS3

SPIRE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPIRE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPIRE2.

Fbxw11

Pechlivanis, M; Samol, A; et al. Identification of a Short Spir Interaction Sequence at the C-terminal End of Formin Subgroup Proteins. JOURNAL OF BIOLOGICAL CHEMISTRY 284:25324-25333(2009).

Quinlan, ME; Hilgert, S; et al. Regulatory interactions between two actin nucleators, Spire and Cappuccino. JOURNAL OF CELL BIOLOGY 179:117-128(2007).

Schumacher, N; Borawski, JM; et al. Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain. GENE EXPRESSION PATTERNS 4:249-255(2004).

CHEUNG, HK; SERANO, TL; et al. EVIDENCE FOR A HIGHLY SELECTIVE RNA TRANSPORT-SYSTEM AND ITS ROLE IN ESTABLISHING THE DORSOVENTRAL AXIS OF THE DROSOPHILA EGG. DEVELOPMENT 114:653-661(1992).