Recombinant Human SPIRE2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SPIRE2-4646H
• Product Overview: SPIRE2 MS Standard C13 and N15-labeled recombinant protein (NP_115827) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: SPIRE2 (Spire Type Actin Nucleation Factor 2) is a Protein Coding gene. Diseases associated with SPIRE2 include Osteogenesis Imperfecta, Type Ii and Osteogenesis Imperfecta, Type I. Among its related pathways are TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is SPIRE1.
• Molecular Mass: 79.5 kDa
• AA Sequence: MARAGSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRGSPGRRLRDTGDLLLRGDGSVGAREPEAAEPATMVVPLASSEAQTVQSLGFAIYRALDWGLDESEERELSPQLERLIDLMANNDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQAMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETPRAELDSLGHTDWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPCILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFPLFSWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVYTLGFESPQRVSAAKTAPIQRRDIFQSLQGPQWQSVEEAFPHIYSHGCVLKDVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYIPNTRTLDFKTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SPIRE2 spire type actin nucleation factor 2 [ Homo sapiens (human) ]
• Official Symbol: SPIRE2
• Synonyms: SPIRE2; spire homolog 2 (Drosophila); protein spire homolog 2; KIAA1832; spir 2; Spir-2; MGC117166
• Gene ID: 84501
• mRNA Refseq: NM_032451
• Protein Refseq: NP_115827
• MIM: 609217
• UniProt ID: Q8WWL2