sqstm1
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  • Official Full Name
  • sequestosome 1
  • Synonyms
Cat.#:SQSTM1-29505THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SQSTM1 Protein, His-tagged
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Cat.#:SQSTM1-2945HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SQSTM1, GST-tagged
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Cat.#:SQSTM1-15964MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SQSTM1 Protein
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Cat.#:SQSTM1-5732RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SQSTM1 Protein
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Cat.#:SQSTM1-4459RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SQSTM1 Protein, His-tagged
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Cat.#:SQSTM1-12388ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SQSTM1
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Cat.#:SQSTM1-2358HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Sequestosome 1, His-tagged
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Cat.#:SQSTM1-1481HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SQSTM1 293 Cell Lysate
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Involved Pathway

SQSTM1 involved in several pathways and played different roles in them. We selected most pathways SQSTM1 participated on our site, such as Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SQSTM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Osteoclast differentiation
LILRB1; PIK3R5; LILRB3; STAT2; TGFBR2; TRAF2; IFNAR2; CAMK4; MAPK9; BLNK

Protein Function

SQSTM1 has several biochemical functions, for example, K63-linked polyubiquitin binding, SH2 domain binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SQSTM1 itself. We selected most functions SQSTM1 had, and list some proteins which have the same functions with SQSTM1. You can find most of the proteins on our site.
Function
Related Protein
Function K63-linked polyubiquitin binding
Related Protein SPRTN; RNF168; ZRANB3; RNF169; ZRANB1B; TNFAIP3; TAB2; UIMC1; ZRANB1; PRPF8
Function SH2 domain binding
Related Protein SKAP1; PAG1; CTR9; LILRB1; NLK; AFAP1L2; MS4A2; ARHGAP5; SYNGR3; JAK2
Function identical protein binding
Related Protein CLDN23; KDM6A; TTR; BCHE; MYBPC3; CLDN17; MCM10; NELL2; PSMD4; LDHA
Function protein binding
Related Protein TMPRSS7; MAP2K3; ABCA1; PLEKHN1; ZFP36; MTCH1; RBM41; IL12B; DKC1; ATP6V1C2
Function protein homodimerization activity
Related Protein MGST1; UGT1A1; FAM109A; TMEM192; GIPC1; MAP3K13; IL6R; CHKA; IRF3; USF2
Function protein kinase C binding
Related Protein SDC4; GLRX3; AKT2; HDAC5; AVPR1A; SQSTM1; DSP; MARCKS; TOP2B; PRKCB
Function protein kinase binding
Related Protein PTPN1; TNNI3; CALM2; Cd24a; PPP1CC; MVP; MAPK4; GDF3; ADCY6; CDKN2D
Function protein serine/threonine kinase activity
Related Protein STK25; SGK2A; MAP3K8; STK40; AKT3; ROCK2B; DMPK; GAK; CSNK1G1; DYRK4
Function receptor tyrosine kinase binding
Related Protein PTPN14; CPNE3; FIZ1; NCK1; FNTA; ANGPT1; PLCG1; PTPN11; PIK3R2; SQSTM1
Function ubiquitin binding
Related Protein SPRTN; KIF18A; UCHL3; C36E6.2; NEDD4; BCL10; OTUB2; SQSTM1; RBCK1; OTUB1A
Function ubiquitin protein ligase binding
Related Protein TSG101; CDC34B; TRAF6; DBT; USP13; ANKRD32; PER1; ARIH1; PIAS1; CUL1
Function zinc ion binding
Related Protein ZDHHC17; SYTL4; MT1G; UBR7; PHC2A; ZNRD1; ADAM18; MMP16; TRIM42; DEF8

Interacting Protein

SQSTM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SQSTM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SQSTM1.
MAP1LC3B; GABARAPL2

SQSTM1 Related Articles

Whyte, MP; Madson, KL; et al. Rapid Skeletal Turnover in a Radiographic Mimic of Osteopetrosis. JOURNAL OF BONE AND MINERAL RESEARCH 29:2601-2609(2014).
Kang, M; Jeong, CW; et al. Inhibition of Autophagy Potentiates Atorvastatin-Induced Apoptotic Cell Death in Human Bladder Cancer Cells in Vitro. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15:8106-8121(2014).