SRM
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Official Full Name
spermidine synthase
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Overview
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor. -
Synonyms
SRM; spermidine synthase; SRML1; SPS1; OTTHUMP00000002170; PAPT; Putrescine aminopropyltransferase; SPDSY; SPEE_HUMAN; Spermidine synthase 1; spermidine synthase-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- SRM Related Articles
SRM involved in several pathways and played different roles in them. We selected most pathways SRM participated on our site, such as Cysteine and methionine metabolism, Arginine and proline metabolism, beta-Alanine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cysteine and methionine metabolism | LDHB;GOT2B;DNMT3A;MDH1AA;DNMT3;AGXT2;MTAP;ADI1;MTR |
| Arginine and proline metabolism | HOGA1;ALDH4A1;GATM;OAT;CNDP1;DAO1;ALDH1B1;SAT2B;CKMT1B |
| beta-Alanine metabolism | ALDH3A2;ALDH2.1;SRM;GAD1B;MLYCD;ALDH9A1A.1;CARNS1;SMS;ALDH9A1 |
| Glutathione metabolism | GGCTB;GGCTA;GSTM2;G6PD;GGT6;GSTA1;MGST1;GSTM6;GSTT2B |
| Metabolic pathways | PLCG1;SGPL1;CS;HADH;PTGS2B;SUCLG2;IDH2;LIPCA;HSD17B10 |
SRM has several biochemical functions, for example, protein binding, protein homodimerization activity, spermidine synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SRM itself. We selected most functions SRM had, and list some proteins which have the same functions with SRM. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CST3;SH3GLB1;KIAA1274;RPL14;EIF2S1;RBX1;CLEC4G;RBM8A;HTR1B |
| protein homodimerization activity | PEX7;HMGCS1;MTMR2;RQCD1;DPP4;BST2;NR6A1A;NLRC4;BCL2L2 |
| spermidine synthase activity |
SRM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRM here. Most of them are supplied by our site. Hope this information will be useful for your research of SRM.
VCAM1; TERF1; DMWD; IKBKE; DDA1; SOX12
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