Recombinant Full Length Human SRM Protein, C-Flag-tagged

• Cat.No.: SRM-1642HFL
• Product Overview: Recombinant Full Length Human SRM Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 33.6 kDa
• AA Sequence: MEPGPDGPAASGPAAIREGWFRETC SLWPGQALSLQVEQLLHHRRSRYQD ILVFRSKTYGNVLVLDGVIQ CTERDEFSYQEMIANLPLCSHPNPR KVLIIGGGDGGVLREVVKHPSVESV VQCEIDEDVIQVSKKFLPGM AIGYSSSKLTLHVGDGFEFMKQNQD AFDVIITDSSDPMGPAESLFKESYY QLMKTALKEDGVLCCQGECQ WLHLDLIKEMRQFCQSLFPVVAYAY CTIPTYPSGQIGFMLCSKNPSTNFQ EPVQPLTQQQVAQMQLKYYN
  SDVHRAAFVLPEFARKALNDVSTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Arginine and proline metabolism, beta-Alanine metabolism, Cysteine and methionine metabolism, Glutathione metabolism, Metabolic pathways

Gene Information

• Gene Name: SRM spermidine synthase [ Homo sapiens (human) ]
• Official Symbol: SRM
• Synonyms: PAPT; SPS1; SPDSY; SRML1
• Gene ID: 6723
• mRNA Refseq: NM_003132.3
• Protein Refseq: NP_003123.2
• MIM: 182891
• UniProt ID: P19623