ssu72
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  • Official Full Name
  • SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
  • Background
  • May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination.
  • Synonyms
  • SSU72; SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae); Ssu72 RNA polymerase II CTD phosphatase homolog (yeast); RNA polymerase II subunit A C-terminal domain phosphatase SSU72; HSPC182; Hypothetical protein FLJ10947; Ssu72 RNA polymerase II CTD phosphatase homolog; CTD phosphatase SSU72; PNAS-120
Cat.#:SSU72-2973HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SSU72, His-tagged
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Cat.#:SSU72-16048MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SSU72 Protein
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Cat.#:SSU72-5764RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SSU72 Protein
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Cat.#:SSU72-4494RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SSU72 Protein, His-tagged
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Cat.#:SSU72-1785CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SSU72
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Cat.#:SSU72-10992ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SSU72
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Cat.#:SSU72-1401HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SSU72 RNA Polymerase II CTD Phosphatase Homolog (S. cerevisiae), His-tagged
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Cat.#:SSU72-1451HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SSU72 293 Cell Lysate
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Involved Pathway

SSU72 involved in several pathways and played different roles in them. We selected most pathways SSU72 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSU72 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
mRNA surveillance pathway
PABPC1L2A; NCBP2; BAT1; PPP1CB; FIP1L1; CASC3; CSTF2T; MAGOHB; PPP1CA; UPF3B

Protein Function

SSU72 has several biochemical functions, for example, CTD phosphatase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SSU72 itself. We selected most functions SSU72 had, and list some proteins which have the same functions with SSU72. You can find most of the proteins on our site.
Function
Related Protein
Function CTD phosphatase activity
Related Protein PPM1M; CTDSPLA; CTDSPLB; RPAP2; SSU72; CTDSP2; CTDSP1; CTDSPL; CTDP1
Function protein binding
Related Protein DNAJC15; HMG20B; DRG2; ASB6; TP53RK; APLF; VAMP4; KPNA3; DEPDC1; TAF6

Interacting Protein

SSU72 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSU72 here. Most of them are supplied by our site. Hope this information will be useful for your research of SSU72.
RAD21; STAG2; UIMC1; MAPK8; MAPK9; SMC1A; SMC3

SSU72 Related Articles

Allepuz-Fuster, P; Martinez-Fernandez, V; et al. Rpb4/7 facilitates RNA polymerase II CTD dephosphorylation. NUCLEIC ACIDS RESEARCH 42:13674-13688(2014).
Rosado-Lugo, JD; Hampsey, M; et al. The Ssu72 Phosphatase Mediates the RNA Polymerase II Initiation-Elongation Transition. JOURNAL OF BIOLOGICAL CHEMISTRY 289:33916-33926(2014).