stx5
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  • Official Full Name
  • syntaxin 5
  • Background
  • This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Synonyms
  • STX5; syntaxin 5; STX5A, syntaxin 5A; syntaxin-5; SED5; syntaxin 5A; STX5A
Cat.#:STX5-5815RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat STX5 Protein
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Cat.#:STX5-4547RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey STX5 Protein, His-tagged
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Cat.#:STX5-1374HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human STX5 293 Cell Lysate
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Involved Pathway

STX5 involved in several pathways and played different roles in them. We selected most pathways STX5 participated on our site, such as SNARE interactions in vesicular transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
SNARE interactions in vesicular transport
STX2; VTI1A; SNAP29; STX6; VAMP3; STX3A; STX5AL; STX1B; GS15; USE1

Protein Function

STX5 has several biochemical functions, for example, SNAP receptor activity, protein N-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX5 itself. We selected most functions STX5 had, and list some proteins which have the same functions with STX5. You can find most of the proteins on our site.
Function
Related Protein
Function SNAP receptor activity
Related Protein STX3; SEC22BA; SNAP23; VAMP2; STX19; STX5AL; GS15; STX4; SNAP23.2; SYBL1
Function protein N-terminus binding
Related Protein ERCC6; VWF; CHMP6; NCOA3; TDRD7; PARP1; NTSR1; ALOX5AP; ERCC3; YWHAQ
Function protein binding
Related Protein UBE2E1; TRIM5; DOK4; EPHB2; WLS; NR4A1; ZNF426; EDAR; BRMS1; OBFC1

Interacting Protein

STX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX5.
TACC1; MAGEA6; STX4; CCDC155; NAPB; SEC22B; SNAP47; COG4; NS