serpinb10
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  • Official Full Name
  • serpin peptidase inhibitor, clade B (ovalbumin), member 10
  • Background
  • The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular;and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor;suppression, apoptosis, and cell migration. Serpins are characterized by a well-conserved tertiary structure that;consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 (PubMed 2690952)). A critical portion of;the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-10 (PI10; SERPINB10) is a;member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a;high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a;serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 (PubMed;9268635)).
  • Synonyms
  • SERPINB10; serpin peptidase inhibitor, clade B (ovalbumin), member 10; PI10, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10; serpin B10; bomapin; protease inhibitor 10 (ovalbumin type; bomapin); PI10; Protease inhibitor 10; Protease inhibitor 10 (ovalbumin type bomapin); Serpin peptidase inhibitor clade B (ovalbumin) member 10; peptidase inhibitor 10; protease inhibitor 10 (ovalbumin type, bomapin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10; PI-10
Cat.#:SERPINB10-862HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SERPINB10 Protein, MYC/DDK-tagged
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Cat.#:Serpinb10-3083MTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Serpinb10, His tagged
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Cat.#:SERPINB10-5340RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SERPINB10 Protein
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Cat.#:SERPINB10-4150RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SERPINB10 Protein, His-tagged
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Cat.#:SERPINB10-6459CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SERPINB10
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Cat.#:SERPINB10-660MCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse SERPINB10 cell lysate
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Involved Pathway

Serpinb10 involved in several pathways and played different roles in them. We selected most pathways Serpinb10 participated on our site, such as Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Serpinb10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Amoebiasis
LAMC2; PIK3CB; TGFB2; ARG2; GNAQ; CD14; ARG1; PIK3R2; LAMB2; TLR2

Protein Function

Serpinb10 has several biochemical functions, for example, peptidase inhibitor activity, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Serpinb10 itself. We selected most functions Serpinb10 had, and list some proteins which have the same functions with Serpinb10. You can find most of the proteins on our site.
Function
Related Protein
Function peptidase inhibitor activity
Related Protein PI15A; SERPINB11; ITIH3; UMODL1; SERPINB1B; SPINK3; KAL1B; COL28A1; Cstb; SERPINA3K
Function serine-type endopeptidase inhibitor activity
Related Protein SERPINB5; SERPINB9; EPPIN; SERPINB2; SPINT2; SERPINB4; APP; PCSK1N; SERPINA3C; SERPINB13

Serpinb10 Related Articles

Lindskog, C; Korsgren, O; et al. Novel pancreatic beta cell-specific proteins: Antibody-based proteomics for identification of new biomarker candidates. JOURNAL OF PROTEOMICS 75:2611-2620(2012).