tcn1
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  • Official Full Name
  • transcobalamin I (vitamin B12 binding protein, R binder family)
  • Background
  • This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
  • Synonyms
  • TCN1; transcobalamin I (vitamin B12 binding protein, R binder family); transcobalamin-1; haptocorin; haptocorrin; TC1; TCI; TC-1
Cat.#:TCN1-1533HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human TCN1 Protein (24-433 aa), His-tagged
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Cat.#:TCN1-1534PTag:His
Source (Host):YeastSpecies:Pig
Product nameRecombinant Pig TCN1 Protein (25-416 aa), His-tagged
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Cat.#:TCN1-569HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TCN1 Protein, His-tagged
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Cat.#:TCN1-27949THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human TCN1
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Cat.#:TCN1-1171HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TCN1 293 Cell Lysate
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Involved Pathway

TCN1 involved in several pathways and played different roles in them. We selected most pathways TCN1 participated on our site, such as Cobalamin (Cbl, vitamin B12) transport and metabolism, Metabolism, Metabolism of vitamins and cofactors, which may be useful for your reference. Also, other proteins which involved in the same pathway with TCN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cobalamin (Cbl, vitamin B12) transport and metabolism
CTRB1; MTRR; LOC100686744; ELA2L; CTRC; TCN1; CBLC-1; ELA2; MMADHC; CD320
Metabolism
GLYATL1; NUDT3; GCHFR; DTYMK; SLC16A1; MED19; DHCR7; UCP2; ABHD10; GYG1B
Metabolism of vitamins and cofactors
KCNG4; CYB5A; CTRC; SLC46A1; CD320; CYB5R3; CTRB1; GSTO2; NAMPT; GPHNA
Metabolism of water-soluble vitamins and cofactors
SLC23A2; SLC2A3; GPHN; SLC5A6A; SLC25A16; SLC25A32; SLC19A2; CBLC-1; SLC25A32B; ELA2
Vitamin B12 Metabolism
TCN1; SAA2; SAA4

Protein Function

TCN1 has several biochemical functions, for example, cobalamin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TCN1 itself. We selected most functions TCN1 had, and list some proteins which have the same functions with TCN1. You can find most of the proteins on our site.
Function
Related Protein
Function cobalamin binding
Related Protein GIF; TCNL; CD320; MUT; CUBN; MMACHC; TCN2; TCN1; LMBRD1

Interacting Protein

TCN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TCN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TCN1.
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