TICAM1

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TICAM1

Official Full Name toll-like receptor adaptor molecule 1
Background Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering
Synonyms TICAM1; toll-like receptor adaptor molecule 1; TIR domain-containing adapter molecule 1; MGC35334; PRVTIRB; TICAM 1; TRIF; putative NF-kappa-B-activating protein 502H; TIR domain containing adaptor inducing interferon-beta; TIR domain-containing adapter p
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TICAM1-1080HCL Recombinant Human TICAM1 293 Cell Lysate HEK293 N/A
    Human TICAM1-648H Recombinant Human TICAM1 Protein, His-tagged E.coli His
    Mouse TICAM1-16772M Recombinant Mouse TICAM1 Protein Mammalian Cell His
    Mouse Ticam1-649M Recombinant Mouse Ticam1 Protein, His-tagged E.coli His
    Cynomolgus Monkey TICAM1-1021C Recombinant Cynomolgus TICAM1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque TICAM1-4712R Recombinant Rhesus monkey TICAM1 Protein, His-tagged Mammalian Cell His
    Chicken TICAM1-3657C Recombinant Chicken TICAM1 Mammalian Cell His
    Zebrafish TICAM1-3910Z Recombinant Zebrafish TICAM1 Mammalian Cell His

    TICAM1 involved in several pathways and played different roles in them. We selected most pathways TICAM1 participated on our site, such as Activated TLR4 signalling, Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TICAM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activated TLR4 signalling SIGIRR; TNIP2; CREB1B; IRAK3; MAPKAPK2B; DUSP7; DHX9; NOD1; PELI1; JUN
    Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon TICAM1; TANK
    Apoptosis AIFM1; NTRK1; BIRC7; DERL3; TNFSF10; HELLS; PRKAR2AA; DIABLO; FADD; HMGB2
    Caspase activation via extrinsic apoptotic signalig pathway DCC; DAPK1; CASP8L1; DAPK3; RNF8; TICAM1
    Chagas disease (American trypanosomiasis) CD3E; CD3D; TNF; IFNG; CCL5; PIK3R3; GNA15; PIK3R1; FAS; MAPK10; IFNGR2
    Cytosolic sensors of pathogen-associated DNA POLR3C; POLR3F; POLR3GLA; NLRP4B; TICAM1; TRIM56; NLRP4E; RIPK3; SAA1; MB21D1
    Disease FGFR1OP2; TAF1L; TNKS2; CUX1; RPL35; VPS37A; PSIP1; ELL; ARF1; CYP11A1
    Diseases associated with the TLR signaling cascade TLR6; TICAM1; TIRAP; TLR10

    TICAM1 has several biochemical functions, for example, protein binding, protein kinase binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TICAM1 itself. We selected most functions TICAM1 had, and list some proteins which have the same functions with TICAM1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding HNRNPK; SEC31A; MYLIPA; U2AF1; KLRB1F; RNF32; DIAPH1; C9orf43; PPP5C; FAM40A
    protein kinase binding CAMK2N2; TRAF3; NPR1; AKAP5; WAS; CCNL2; TP73; NEFH; FOXO3; LATS1
    signal transducer activity TAAR14I; GNGT1; TACR1B; OPN4A; OPN1SW1; TMED4; ADRA1BB; TSPAN6; GPR31B; CHRM5A

    TICAM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TICAM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TICAM1.

    TBK1; TNFAIP3; TICAM2; PIAS4; SRSF4; KIF21B; Immt; TANK; CDCA5; CEP170P1; MKNK2

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