ticam2
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  • Official Full Name
  • toll-like receptor adaptor molecule 2
  • Background
  • TIRP is a Toll/interleukin-1 receptor (IL1R; MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4; MIM 603030).
  • Synonyms
  • TICAM2; toll-like receptor adaptor molecule 2; TIR domain-containing adapter molecule 2; TICAM 2; TIRP; TRAM; cytoplasmic adaptor; TRIF-related adaptor molecule; NF-kappa-B-activating protein 502; toll-like receptor adaptor protein 3; putative NF-kappa-B-
Cat.#:TICAM2-646HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TICAM2 Protein, His-tagged
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Cat.#:Ticam2-647MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ticam2 Protein, His/GST-tagged
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Cat.#:TICAM2-3230HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TICAM2, GST-tagged
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Cat.#:TICAM2-16773MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TICAM2 Protein
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Cat.#:TICAM2-1022CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus TICAM2 Protein, His-tagged
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Cat.#:TICAM2-4713RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TICAM2 Protein, His-tagged
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Cat.#:TICAM2-1079HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TICAM2 293 Cell Lysate
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Involved Pathway

TICAM2 involved in several pathways and played different roles in them. We selected most pathways TICAM2 participated on our site, such as NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TICAM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
NF-kappa B signaling pathway
GM13304; RELB; LTA; TRAF6; LYN; CCL21B; PTGS2; LTBR; XIAP; LY96
Toll-like receptor signaling pathway
CCL3; CCL5; NFKB1; PIK3CA; MAP2K2A; IFNA2; IL1B; CD86; TLR1LB; MAP2K1
Pertussis
ITGB2L; C1QA; IRF8; AMCF-II; C4BP; MAPK8; C4BPA; IL1B; CFL2; TNF
Hepatitis B
SMAD4; BAX; IRF7; DDX3X; IFNA17; CREB3L2; TGFB2; IRF3; DDX58; PIK3CD

Protein Function

TICAM2 has several biochemical functions, for example, phospholipid binding, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TICAM2 itself. We selected most functions TICAM2 had, and list some proteins which have the same functions with TICAM2. You can find most of the proteins on our site.
Function
Related Protein
Function phospholipid binding
Related Protein LPAR3; PSD2; PLA2G15; AGAP1; BAIAP2L2; AMPH; SPTBN2; SDPR; GOT2; SMURF1
Function protein binding
Related Protein ATG9A; CDK16; TMEM174; PDE3B; BNIP2; SKP2; TBCA; PPP1R16B; LRP5; TARSL2
Function signal transducer activity
Related Protein GNA15.1; LGR4; PLCXD3; PLCH2; NPFFR1L2; CELSR1; LGALS9; OPN4B; GULP1; ADRB2A

Interacting Protein

TICAM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TICAM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TICAM2.
MEOX2; C; TLR4; IL1R1; TIRAP; TICAM1; IL1RAP; TRAF6; PIAS2; FTH1; Smad6