Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

TLR9

  • Official Full Name

    toll-like receptor 9

  • Overview

    Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. TLR9 has also been designated as CD289 (cluster of differentiation 289).
  • Synonyms

    CD 289; CD289; TLR 9; TLR9; TLR9_HUMAN; Toll like receptor 9; Toll like receptor 9 isoform A precursor; Toll like receptor 9 isoform B; Toll-like receptor 9; CD289 antigen;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rabbit
  • Rat
  • Rhesus Macaque
  • Rhesus monkey
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Fc
  • hIgG1
  • hIgG4
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TLR9-48H Recombinant Human TLR9 protein E.coli N/A
Human TLR9-452H Recombinant Human TLR9 protein Wheat Germ N/A
Human TLR9-695H Recombinant Human TLR9 protein, His-tagged E.coli His Thr28~Ser362
Human TLR9-1042HCL Recombinant Human TLR9 293 Cell Lysate HEK293 N/A
Human TLR9-573HF Recombinant Full Length Human TLR9 Protein In Vitro Cell Free System 1032 amino acids
Human TLR9-115H Recombinant Human TLR9 Protein, His-tagged E.coli His
Human TLR9-0930H Recombinant Human TLR9 Protein (Asn64-Glu189), N-His tagged E.coli N-His Asn64-Glu189
Human TLR9-4946H Recombinant Human TLR9 Protein (Met1-Cys818), C-His tagged Mammalian cells C-His Met1-Cys818
Human TLR9-0183H Active Recombinant Human TLR9 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Mouse Tlr9-372M Active Recombinant Mouse Tlr9 protein, Fc-tagged CHO Fc
Mouse Tlr9-696M Recombinant Mouse Tlr9 protein, His & GST-tagged E.coli His/GST Leu26~Asn332 (Accession# Q9EQU3)
Mouse TLR9-16831M Recombinant Mouse TLR9 Protein Mammalian Cell His
Mouse TLR9-9240M Recombinant Mouse TLR9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TLR9-9240M-B Recombinant Mouse TLR9 Protein Pre-coupled Magnetic Beads HEK293
Rat Tlr9-697R Recombinant Rat Tlr9 protein, His & T7-tagged E.coli His/T7 Leu496~Val772
Rhesus monkey TLR9-1683R Recombinant Rhesus Monkey TLR9 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey TLR9-1682R Recombinant Rhesus Monkey TLR9 Protein HEK293 N/A
Rhesus monkey TLR9-1684R Recombinant Rhesus Monkey TLR9 Protein, hIgG4-tagged HEK293 hIgG4
Rabbit TLR9-422R Recombinant Rabbit TLR9 Protein, His-tagged E.coli N-His Leu864-Asp1012
Rhesus Macaque TLR9-4738R Recombinant Rhesus monkey TLR9 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TLR9-4552R Recombinant Rhesus Macaque TLR9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TLR9-4552R-B Recombinant Rhesus Macaque TLR9 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish TLR9-7078Z Recombinant Zebrafish TLR9 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TLR9 Related Articles
  • TLR9 Related Research Area

TLR9 involved in several pathways and played different roles in them. We selected most pathways TLR9 participated on our site, such as Toll-like receptor signaling pathway, Chagas disease (American trypanosomiasis), African trypanosomiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLR9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Toll-like receptor signaling pathwayTLR1;PIK3CB;TLR2-2;IFNA4;CD80;IFNA10;TLR4BB;MAPK8;TLR5
Chagas disease (American trypanosomiasis)GNA14;PPP2CB;PIK3CB;PLCB3;PPP2R2C;AKT1;TRAF6;IL-8;IL1B
African trypanosomiasisPLCB1;HBA2;THOP1;IDO2;PLCB4;IFNG;ICAM1;Fasl;IL12A
MalariaTNF;IFNG;VCAM1;ITGB2;HBB;TGFB1;ICAM1;TLR9;LRP1
TuberculosisItgam&Itgb2;IFNA13;IL10RB;Ifna15;RHOA;IL10RA;RIPK2;ATP6V1H;IFNA10
MeaslesIFNA6;EIF3H;IL12B;NFKBIA;FYN;AKT1;MSN;TP53;TLR4
Herpes simplex infectionIL12B;IFNA13;IL15;TAF5L;TLR9;EIF2AK1;IFNA8;SKP2;CASP3A

TLR9 has several biochemical functions, for example, interleukin-1 receptor binding, siRNA binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TLR9 itself. We selected most functions TLR9 had, and list some proteins which have the same functions with TLR9. You can find most of the proteins on our site.

Function Related Protein
interleukin-1 receptor bindingIL36RN;IL36A;IL36B;IL1RAP;TLR9;IL1B;IRAK1;IL1F10;IRAK4
siRNA bindingTARBP2;MECP2;AGO2;DICER1;TLR9;TLR7
transmembrane signaling receptor activityCD79B;EMR4;FZD3B;GP6;CD69;GPR113;GIPR;KLRB1;OR4D6

TLR9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TLR9 here. Most of them are supplied by our site. Hope this information will be useful for your research of TLR9.

NCK1; CLGN; TRAF3; STK11IP; TOLLIP; UNC93B1; UGGT1; PALD1

Li, XY; Yue, Y; et al. Extracellular, but not intracellular HMGB1, facilitates self-DNA induced macrophage activation via promoting DNA accumulation in endosomes and contributes to the pathogenesis of lupus nephritis. MOLECULAR IMMUNOLOGY 65:177-188(2015).
Chan, E; Kwak, EL; et al. Open-label phase 1b study of FOLFIRI plus cetuximab plus IMO-2055 in patients with colorectal cancer who have progressed following chemotherapy for advanced or metastatic disease. CANCER CHEMOTHERAPY AND PHARMACOLOGY 75:701-709(2015).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
In which cellular compartments is TLR9 primarily located? 12/24/2021

TLR9 is primarily located in endosomes and lysosomes.

What is the primary role of TLR9 in the immune system? 07/08/2021

TLR9 detects unmethylated CpG DNA from bacteria and viruses, activating immune responses.

Are there therapeutic strategies targeting TLR9? 02/26/2021

Therapeutic strategies may target TLR9 to enhance vaccine efficacy or modulate autoimmune responses.

How is TLR9 implicated in autoimmune diseases? 08/01/2020

Dysregulation of TLR9 can contribute to the development of autoimmune diseases.

How does TLR9 recognize and respond to foreign DNA? 07/14/2019

It recognizes foreign DNA based on specific nucleotide patterns, initiating signaling cascades.

What types of pathogens does TLR9 help defend against? 04/05/2019

It plays a role in defending against bacterial and viral infections.

What downstream signaling pathways does TLR9 activate? 12/17/2018

TLR9 activation leads to NF-κB activation and cytokine production.

Customer Reviews (3)

Write a review
Reviews
02/27/2021

    Fantastic results, very reliable.

    08/08/2020

      Great quality, excellent service.

      01/24/2019

        Satisfied with the purchase.

        Ask a Question for All TLR9 Products

        Required fields are marked with *

        My Review for All TLR9 Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends