• Official Full Name
  • transmembrane protein 123
  • Background
  • This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
  • Synonyms
  • TMEM123; transmembrane protein 123; porimin; KCT3; pro oncosis receptor inducing membrane injury gene; Keratinocytes associated transmembrane protein 3; Pro oncosis receptor inducing membrane injury; Serine/threonine rich receptor; KCT-3; OTTHUMP00000235711; OTTHUMP00000235712; serine/threonine-rich receptor; pro-oncosis receptor inducing membrane injury; keratinocytes-associated transm; PORMIN
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TMEM123 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TMEM123 Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TMEM123 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TMEM123
Source (Host):Species:Human
Product nameRecombinant Human TMEM123 cell lysate

Protein Function

TMEM123 has several biochemical functions, for example, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TMEM123 itself. We selected most functions TMEM123 had, and list some proteins which have the same functions with TMEM123. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein CD8B; RPS6KC1; ATP2B1; COL18A1; GGN; LRFN2; WWC1; SRSF5; IFITM3; FSTL5
Function receptor activity
Related Protein EDAR; CD200R4; LILRA3; VMN1R46; KLRB1F; ADIPOR1B; MRC1; FPR3; CXCR3; NOTCH4

Interacting Protein

TMEM123 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMEM123 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMEM123.
MAGEA11; q81y32_bacan; MAGEA11