Recombinant Human TMEM123 cell lysate

• Cat.No.: TMEM123-1790HCL

Specification

• Description: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: TMEM123 transmembrane protein 123 [ Homo sapiens ]
• Official Symbol: TMEM123
• Synonyms: TMEM123; transmembrane protein 123; porimin; KCT3; PORIMIN; pro oncosis receptor inducing membrane injury gene; KCT-3; serine/threonine-rich receptor; pro oncosis receptor inducing membrane injury; pro-oncosis receptor inducing membrane injury; keratinocytes associated transmembrane protein 3; keratinocytes-associated transmembrane protein 3; PORMIN
• Gene ID: 114908
• mRNA Refseq: NM_052932
• Protein Refseq: NP_443164
• MIM: 606356
• UniProt ID: Q8N131
• Chromosome Location: 11q22.1
• Function: receptor activity