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TMPRSS6

Official Full Name

transmembrane protease, serine 6
Overview

The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Synonyms

TMPRSS6; transmembrane protease, serine 6; IRIDA; transmembrane protease serine 6; matriptase-2; type II transmembrane serine protease 6; membrane-bound mosaic serine proteinase matriptase-2;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Mouse

Source

E.coli
HEK293
Insect Cell
Mamanlian cells
Wheat Germ

Tag

DDK
Flag
GST
His|Myc
N/A
N
His

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TMPRSS6-127H	Recombinant Human TMPRSS6 protein, DDK-tagged	Insect Cell	DDK	77-811aa	Inquiry
Human	TMPRSS6-126H	Recombinant Human TMPRSS6 protein, GST-tagged	Wheat Germ	GST	1 a.a. - 461 a.a.	Inquiry
Human	TMPRSS6-1799HCL	Recombinant Human TMPRSS6 cell lysate		N/A		Inquiry
Human	TMPRSS6-430H	Recombinant Human TMPRSS6 Protein, His&GST-tagged	E.coli	N-His&GST	Ala608-Thr811	Inquiry
Human	TMPRSS6-3247HFL	Recombinant Full Length Human TMPRSS6 protein, Flag-tagged	Mamanlian cells	Flag		Inquiry
Mouse	TMPRSS6-17123M	Recombinant Mouse TMPRSS6, His-MYC-tagged	HEK293	His/Myc		Inquiry
Mouse	TMPRSS6-2746M	Recombinant Mouse TMPRSS6 Protein (81-811 aa), His-Myc-tagged	Insect Cell	His/Myc	81-811 aa	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TMPRSS6 Related Articles

TMPRSS6 involved in several pathways and played different roles in them. We selected most pathways TMPRSS6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TMPRSS6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TMPRSS6 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMPRSS6 itself. We selected most functions TMPRSS6 had, and list some proteins which have the same functions with TMPRSS6. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	FSTL1A;CPS1;NCALDB;PCDHGC5;CABP1;CALR3B;DSG1;NUCB2B;FBLN2

TMPRSS6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMPRSS6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMPRSS6.

Canavese, C; Quaglia, M; et al. Very high frequency of TMPRSS6 gene variations in iron deficiency anaemia of patients with polyendocrine autoimmune syndromes: more than a casual association?. BRITISH JOURNAL OF HAEMATOLOGY 161:147-150(2013).

Chen, WJ; Sun, CC; et al. A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum. HAEMATOLOGICA 98:296-304(2013).