Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

TRIM5

  • Official Full Name

    tripartite motif containing 5

  • Overview

    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
  • Synonyms

    TRIM5; tripartite motif containing 5; tripartite motif-containing protein 5; RNF88; TRIM5alpha; tripartite motif protein TRIM; tripartite motif protein TRIM5; ring finger protein 88; tripartite motif containing 5 transcript variant iota; tripartite motif;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • B2M
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TRIM5-444H Recombinant Human TRIM5 Protein, His-tagged E.coli His
Human TRIM5-770HCL Recombinant Human TRIM5 293 Cell Lysate HEK293 N/A
Human TRIM5-3390H Recombinant Human TRIM5 protein, His-tagged E.coli His 136-224 aa
Human TRIM5-2466H Recombinant Human TRIM5 protein, His-tagged E.coli His 1-493aa
Human TRIM5-4852H Recombinant Human TRIM5 protein, His-B2M-tagged E.coli His-B2M 1-493aa
Mouse Trim5-1696M Recombinant Mouse Trim5 protein, His-tagged E.coli His Ala2~Ser218
Cynomolgus Monkey TRIM5-1049C Recombinant Cynomolgus TRIM5 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey TRIM5-792C-B Recombinant Cynomolgus Monkey TRIM5 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey TRIM5-792C Recombinant Cynomolgus Monkey TRIM5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TRIM5-4970R Recombinant Rhesus monkey TRIM5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TRIM5-4784R-B Recombinant Rhesus Macaque TRIM5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TRIM5-4784R Recombinant Rhesus Macaque TRIM5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TRIM5 Related Articles
  • TRIM5 Related Research Area

TRIM5 involved in several pathways and played different roles in them. We selected most pathways TRIM5 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine Signaling in Immune systemPHB;PEA15A;HAVCR2;FRS2A;FGF10B;TRIM17;IFITM3;IFIT8;UBE2V1
Immune SystemDUSP3;SEC61B;UFL1;DEFB4A;POLR3F;TAX1BP1B;DEFB129;LRSAM1;SLAMF6
Interferon SignalingXAF1;IFITM2;IRF4;TRIM14;TRIM62;TRIM10;MX2;TRIM5;IFIT11
Interferon gamma signalingTRIM14;GBP1;TRIM17;TRIM22;TRIM46;IRF6;TRIM62;TRIM26;GBP6

TRIM5 has several biochemical functions, for example, identical protein binding, ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM5 itself. We selected most functions TRIM5 had, and list some proteins which have the same functions with TRIM5. You can find most of the proteins on our site.

Function Related Protein
identical protein bindingPACSIN2;TP63;MAP1S;DYNLRB1;LYZ2;CLDN10;NOD1;CLDN16;SAFB2
ligase activityRNF19B;HECW1;TRIM4;TRIM71;RC3H2;TRIML1;CCNB1IP1;RNF146;WWP1
protein bindingRAD23B;HDAC7;CSNK1E;SLC11A2;MRPL27;SIRT1;IQUB;GPS2;ZMYM2
protein binding, bridgingSLC9A1;ADAP2;SPRR1B;FBXW7;CAV1;NUFIP1;EVPL;ANK2;TRIM5
protein homodimerization activityCAMK2A;DHDPSL;LDB1;S100A16;NFKB1;DROSHA;TLR13;DPP4;CCBL2
protein kinase bindingPPP1R12A;PDCD10;KAT2B;KCNH1;PXN;GCSAM;CAMK2N1;EEF1A2;RHOD
signaling pattern recognition receptor activityFCN1;MARCO;TLR2;DMBT1;COLEC12;CLEC7A;TRIM5
ubiquitin-protein transferase activityRNF11;FBXL14A;CBLL1;UBE2H;RNF168;PRP19;UBE2T;SIAH1A;TRAF4
zinc ion bindingADH1B;ZCCHC4;MBD1;SERPINB1A;EHMT1A;CPO;RTN4IP1;ZDHHC22;TAB2

TRIM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM5.

TRIM32; ZWINT; SNAI1; HIP2; UBE2D1; MNAT1; UBE2D3; UBE2N; UBE2H; MKRN3; UBE2V1; UBE2V2; UBE2U; TRIM34

Ferguson, D; Mattiuzzo, G; et al. Early Biodistribution and Persistence of a Protective Live Attenuated SIV Vaccine Elicits Localised Innate Responses in Multiple Lymphoid Tissues. PLOS ONE 9:-(2014).
Schneider, A; Wagner, A; et al. Problems and Prospects of Gene Therapy Against HIV. PHARMACEUTICAL CHEMISTRY JOURNAL 47:627-635(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All TRIM5 Products

Required fields are marked with *

My Review for All TRIM5 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends