• Official Full Name
  • tRNA splicing endonuclease 15 homolog (S. cerevisiae)
  • Background
  • tRNA splicing is a fundamental process required for cell growth and division. SEN15 is a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns, the first step in tRNA splicing (Paushkin et al., 2004 (PubMed 15109492)).
  • Synonyms
  • TSEN15; tRNA splicing endonuclease 15 homolog (S. cerevisiae); C1orf19, chromosome 1 open reading frame 19; tRNA-splicing endonuclease subunit Sen15; Chromosome 1 open reading frame 19; Chromosome 1 open reading frame 19, isoform CRA_c; hsSen15; sen15; SEN15 homolog; tRNA intron endonuclease Sen15; tRNA splicing endonuclease subunit Sen15; OTTHUMP00000033516; OTTHUMP00000228759; OTTHUMP00000228760; OTTHUMP00000228761; OTTHUMP00000228762; tRNA-intron endonuclease Sen15; C1orf19
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human tRNA Splicing Endonuclease 15 Homolog (S. cerevisiae), His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TSEN15, His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TSEN15 tRNA splicing endonuclease subunit, His-tagged
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TSEN15
Source (Host):Species:Human
Product nameRecombinant Human TSEN15 293 Cell Lysate

Involved Pathway

TSEN15 involved in several pathways and played different roles in them. We selected most pathways TSEN15 participated on our site, such as Gene Expression, tRNA processing, tRNA processing in the nucleus, which may be useful for your reference. Also, other proteins which involved in the same pathway with TSEN15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
HNRNPUL1; ZNF468; ZNF697; ZFP37; TFB2M; MBD3B; NR1I3; RRP8; ZNF567; MTA2
tRNA processing
NSUN2; METTL1; ADAT1; TRMT61A; CCDC76; TRMT44; RPP38; C14orf166; TRMT112; THG1L
tRNA processing in the nucleus
RPP30; TSEN15; ZBTB8OS; ELAC2; RPP40; RPP14; C22orf28; FAM98B; POP1; TSEN54

Protein Function

TSEN15 has several biochemical functions, for example, tRNA-intron endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TSEN15 itself. We selected most functions TSEN15 had, and list some proteins which have the same functions with TSEN15. You can find most of the proteins on our site.
Related Protein
Function tRNA-intron endonuclease activity
Related Protein TSEN2; TSEN34; TSEN15

Interacting Protein

TSEN15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSEN15 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSEN15.