Recombinant Human TSEN15, His-tagged

• Cat.No.: TSEN15-997H
• Product Overview: Recombinant humanTSEN15 protein, fused to His-tag at N-terminus, was expressed in E. coliand purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: TSEN15 belongs tothe SEN15 family. tRNA splicing is a fundamental process required for cellgrowth and division. TSEN15 is a subunit of the tRNA splicing endonuclease.It cleaves pre-tRNA at the 5" and 3" splice sites to release the intron.
• Application: SDS-PAGE
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl.
• Molecular Weight: 20.9 kDa (191aa),confirmed by MALDI-TOF
• Purity: > 90% by SDS-PAGE
• Concentration: 0.5 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSHMEERGDSEPT PGCSGLGPDG VRGFGDGGGA PSWAPEDAWM GTHPKYLEMMELDIGDATHV YVAFLVYLDL MESKSWHEVN CVGLPELQLI CLVGTEIEGE GLQTVVPTPI TASLSHNRIREILKASRKLQ GDPDLPMSFT LAIVESDSTI VYYKLTDGFM LPDPQNISLR R
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: TSEN15

Gene Information

• Gene Name: TSEN15 tRNA splicing endonuclease15 homolog (S. cerevisiae) [ Homo sapiens ]
• Synonyms: TSEN15; tRNAsplicing endonuclease 15 homolog (S. cerevisiae); sen15;HsSEN15; SEN15; C1orf19; tRNA-splicing endonuclease subunit Sen15;hsSen15;SEN15 homolog; OTTHUMP00000033516; OTTHUMP00000228759;OTTHUMP00000228760;OTTHUMP00000228761; OTTHUMP00000228762; tRNA-intronendonuclease Sen15;chromosome 1 open reading frame 19
• Gene ID: 116461
• mRNA Refseq: NM_052965
• Protein Refseq: NP_443197
• MIM: 608756
• UniProt ID: Q8WW01
• Chromosome Location: 1q25