tlr9
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  • Official Full Name
  • toll-like receptor 9
  • Background
  • Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. TLR9 has also been designated as CD289 (cluster of differentiation 289).
  • Synonyms
  • CD 289; CD289; TLR 9; TLR9; TLR9_HUMAN; Toll like receptor 9; Toll like receptor 9 isoform A precursor; Toll like receptor 9 isoform B; Toll-like receptor 9; CD289 antigen
Cat.#:TLR9-452HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human TLR9 protein
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Cat.#:TLR9-48HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TLR9 protein
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Cat.#:TLR9-695HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TLR9 protein, His-tagged
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Cat.#:TLR9-16831MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TLR9 Protein
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Cat.#:Tlr9-372MTag:Fc
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Tlr9 protein, Fc-tagged
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Cat.#:Tlr9-696MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Tlr9 protein, His & GST-tagged
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Cat.#:Tlr9-697RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Tlr9 protein, His & T7-tagged
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Cat.#:TLR9-1682RTag:
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey TLR9 Protein
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Cat.#:TLR9-1683RTag:hIgG1
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey TLR9 Protein, hIgG1-tagged
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Cat.#:TLR9-1684RTag:hIgG4
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey TLR9 Protein, hIgG4-tagged
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Cat.#:TLR9-4738RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TLR9 Protein, His-tagged
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Cat.#:TLR9-7078ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TLR9
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Cat.#:TLR9-1042HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TLR9 293 Cell Lysate
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Involved Pathway

TLR9 involved in several pathways and played different roles in them. We selected most pathways TLR9 participated on our site, such as Toll-like receptor signaling pathway, Chagas disease (American trypanosomiasis), African trypanosomiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLR9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Toll-like receptor signaling pathway
MAP3K7; CD14; AKT2L; IL1B; IL-8; MAPK12A; IFNA4; IL12BA; NFKBIAA; MAPK1
Chagas disease (American trypanosomiasis)
ACE; CD3E; TLR2; IFNGR2; CCL5; IL1B; Ccl12; CD3G; PLCB3; IFNB1
African trypanosomiasis
THOP1; MYD88; HBA1; IDO1; APOA1; VCAM1; TLR9; HBB-B1; PLCB2; PLCB4
Malaria
IL6; HBA1; IL1B; CD81; TGFB2; CCL2; SDC2; KLRB1; HBB; CSF3
Tuberculosis
Cd209g; CAMK2G; BAD; Pla2r1; HLA-DRB5; ATP6AP1; HLA-DRB3; ATP6V0A1; IFNA12; ITGB2
Measles
CD3E; EIF2AK4; PRKCQ; EIF2AK1; OAS2; IFNGR2; IL12B; CD46; OAS1B; Ifna15
Herpes simplex infection
PPP1CAA; LOC100033925; EEF1D; SRSF4; MHC1UEA; SRSF2A; H2-Q10; TRAF6; PTPN11; TLR2-2

Protein Function

TLR9 has several biochemical functions, for example, interleukin-1 receptor binding, siRNA binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TLR9 itself. We selected most functions TLR9 had, and list some proteins which have the same functions with TLR9. You can find most of the proteins on our site.
Function
Related Protein
Function interleukin-1 receptor binding
Related Protein IL1RAP; TLR9; IL1A; IL36B; IL37; IL1RN; IL36RN; IRAK4; IRAK1; Il1f6
Function siRNA binding
Related Protein MECP2; TLR7; AGO2; TARBP2; TLR9; DICER1
Function transmembrane signaling receptor activity
Related Protein OR6K3; P2RX6; NRXN2; CD3G; TLR2-1; ERBB2; Fzd4; DARC; NCR2; BAI2

Interacting Protein

TLR9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TLR9 here. Most of them are supplied by our site. Hope this information will be useful for your research of TLR9.
NCK1; CLGN; TRAF3; STK11IP; TOLLIP; UNC93B1; UGGT1; PALD1

TLR9 Related Articles

Li, XY; Yue, Y; et al. Extracellular, but not intracellular HMGB1, facilitates self-DNA induced macrophage activation via promoting DNA accumulation in endosomes and contributes to the pathogenesis of lupus nephritis. MOLECULAR IMMUNOLOGY 65:177-188(2015).
Chan, E; Kwak, EL; et al. Open-label phase 1b study of FOLFIRI plus cetuximab plus IMO-2055 in patients with colorectal cancer who have progressed following chemotherapy for advanced or metastatic disease. CANCER CHEMOTHERAPY AND PHARMACOLOGY 75:701-709(2015).