UBE2T Protein, ubiquitin-conjugating enzyme E2T (putative)

UBE2T

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UBE2T

Official Full Name ubiquitin-conjugating enzyme E2T (putative)
Background The covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is;transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a;ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3) (Machida et al., 2006 (PubMed;16916645)).
Synonyms UBE2T; ubiquitin-conjugating enzyme E2T (putative); ubiquitin-conjugating enzyme E2 T; HSPC150; ubiquitin-protein ligase T; ubiquitin carrier protein T; ubiquitin conjugating enzyme; cell proliferation-inducing gene 50 protein; HSPC150 protein similar to ubiquitin-conjugating enzyme; PIG50
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBE2T-561H Recombinant Human UBE2T Protein (Met1-Val197), His-tagged E.coli His
    Human UBE2T-141H Recombinant Human UBE2T E.coli N/A
    Human UBE2T-142H Recombinant Human UBE2T, His-SUMO-tagged E.coli His/SUMO
    Human UBE2T-2355H Recombinant Human UBE2T, His-tagged E.coli His
    Human UBE2T-3546H Recombinant Human UBE2T, GST-tagged E.coli GST
    Human UBE2T-561HCL Recombinant Human UBE2T 293 Cell Lysate HEK293 N/A
    Mouse UBE2T-17733M Recombinant Mouse UBE2T Protein Mammalian Cell His
    Zebrafish UBE2T-4665Z Recombinant Zebrafish UBE2T Mammalian Cell His

    UBE2T involved in several pathways and played different roles in them. We selected most pathways UBE2T participated on our site, such as Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2T were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fanconi anemia pathway FANCM; WDR48; PALB2; BRCA1; FANCI; BRCA2; FANCE; BLM; TOP3B; FANCA

    UBE2T has several biochemical functions, for example, ATP binding, chromatin binding, ubiquitin conjugating enzyme activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2T itself. We selected most functions UBE2T had, and list some proteins which have the same functions with UBE2T. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PLK2; ATP1A1A.1; HIPK2; PFKFB2A; GM7168; FGFR4; DGKB; STK32A; XRCC5; ASS1
    chromatin binding GATA6; MCMBP; TOX3; CBX7; NCOA3; REL; TRIM37; SP3; HESX1; HDGF2
    ubiquitin conjugating enzyme activity UBE2D2A; UBE2G2; UBE2A; UBE2E2; UBE2N; UBE2QL1; UBE2E1; CDC34; UBE2D1; UBE2D4
    ubiquitin protein ligase activity HECTD3; BFAR; MDM2; UBE2U; HACE1; CCNC; MARCH1; RNF41; TOPORS; UBE2V2
    ubiquitin protein ligase binding BAG4; SKI; ARRB2; TRIB2; TANK; SNCAIP; ACVR1B; PDE4D; SPOP; UBXN6
    ubiquitin-protein transferase activity DZIP3; ZNRF3; RNF213; MYLIP; UBE2A; FBXO9; RNF43; UBE2D1; MGRN1; TRIM32

    UBE2T has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2T here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2T.

    ARIH2; UBE2V1; MGRN1; TRIM27; PCGF2; RNF144B; LNX2; RNF128; MARCH5; AMFR; SNURF

    Renaudin, X; Guervilly, JH; et al. Proteomic analysis reveals a FANCA-modulated neddylation pathway involved in CXCR5 membrane targeting and cell mobility. JOURNAL OF CELL SCIENCE 127:3546-3554(2014).
    Hodson, C; Purkiss, A; et al. Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection. STRUCTURE 22:337-344(2014).

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