UBQLN1

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UBQLN1

Official Full Name ubiquilin 1
Background This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimers and Parkinsons disease. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms UBQLN1; ubiquilin 1; ubiquilin-1; DA41; DSK2; PLIC 1; XDRP1; hPLIC-1; protein linking IAP with cytoskeleton 1; UBQN; PLIC-1; FLJ90054
    • Species :
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBQLN1-279H Recombinant Human UBQLN1 Protein, His-tagged HEK293 His
    Human UBQLN1-276H Recombinant Human UBQLN1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human UBQLN1-277H Recombinant Human UBQLN1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human UBQLN1-278H Recombinant Human UBQLN1 protein, GST-tagged Wheat Germ GST
    Human UBQLN1-3558H Recombinant Human UBQLN1, GST-tagged E.coli GST
    Human UBQLN1-546HCL Recombinant Human UBQLN1 293 Cell Lysate HEK293 N/A
    Rat UBQLN1-6411R Recombinant Rat UBQLN1 Protein Mammalian Cell His

    UBQLN1 involved in several pathways and played different roles in them. We selected most pathways UBQLN1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBQLN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein processing in endoplasmic reticulum UBE2D4; NFE2L2; PDIA4; HSPA6; UBE2J1; UBE2G2; DNAJB12; MAN1A; LMAN1L; MBTPS1

    UBQLN1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by UBQLN1 itself. We selected most functions UBQLN1 had, and list some proteins which have the same functions with UBQLN1. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding SDK2; SERPINA1E; TTC32; MID1; UBQLN4; FHOD1; P2RX2; KIRRELA; TPRG1L; PTPRG
    kinase binding JAKMIP3; PFKM; PRKAA1; CDC37; DLG1; EMP2; UBQLN1; RB1; PTPN22; GFAP
    polyubiquitin binding DZIP3; UBQLN1; PSMD4B; RAD23B; BRE; UBXN1; HDAC6; UBQLN4; VCP; BAG6
    protein binding TRAF3IP2; NR2C2AP; CDK5; FKBP1A; ACY3; SIP1; TSPAN1; NFKBIA; BLZF1; NIPAL3

    UBQLN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBQLN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBQLN1.

    SERPINI2; HSPA13; UBQLN4; 3537

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