vamp4
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  • Official Full Name
  • vesicle-associated membrane protein 4
  • Background
  • Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport.
  • Synonyms
  • VAMP4; vesicle-associated membrane protein 4; VAMP 24; VAMP 4; VAMP24; VAMP4 protein; Vesicle associated membrane protein 4; Vesicle associated membrane protein 4 isoform CRA a; Vesicle associated membrane protein 4 isoform CRA b; VAMP-4
Cat.#:VAMP4-31699THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VAMP4, His-tagged
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Cat.#:VAMP4-3641HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human VAMP4, GST-tagged
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Cat.#:VAMP4-819HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human VAMP4
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Cat.#:VAMP4-10998ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish VAMP4
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Cat.#:VAMP4-484HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Vesicle-associated Membrane Protein 4, His-tagged
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Cat.#:VAMP4-436HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human VAMP4 293 Cell Lysate
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Involved Pathway

VAMP4 involved in several pathways and played different roles in them. We selected most pathways VAMP4 participated on our site, such as SNARE interactions in vesicular transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with VAMP4 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
SNARE interactions in vesicular transport
GOSR1; STX5AL; STX2A; SNAP29; VTI1B; SEC22BA; STX11A; STX5A; STX4; BET1

Protein Function

VAMP4 has several biochemical functions, for example, SNAP receptor activity, SNARE binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VAMP4 itself. We selected most functions VAMP4 had, and list some proteins which have the same functions with VAMP4. You can find most of the proteins on our site.
Function
Related Protein
Function SNAP receptor activity
Related Protein STX11A; VAMP4; STX1B; STX11B.2; SEC22BB; SEC22A; BET1L; SNAP23.2; SNAP25B; YKT6
Function SNARE binding
Related Protein SEC22C; EXOC3; SEC22BA; STX7; VAMP7; TNFAIP2; UNC13A; SEC22A; SNAPIN; VAMP3
Function protein binding
Related Protein FAS; HER11; HMGN4; PAK3; EIF3H; Raet1a; SYN1; ZNF263; FAM133A; C10orf119

Interacting Protein

VAMP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VAMP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of VAMP4.
STX4; STX12; CCDC155; SNAP47; STX7; STX6; Ap1g1; Ap1m1; AP1B1; SCAMP5; AP1S3