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WHSC1L1

  • Official Full Name

    Wolf-Hirschhorn syndrome candidate 1-like 1

  • Overview

    This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described.
  • Synonyms

    WHSC1L1; Wolf-Hirschhorn syndrome candidate 1-like 1; histone-lysine N-methyltransferase NSD3; FLJ20353; NSD3; DKFZp667H044; Histone lysine N methyltransferase NSD3; MGC126766; MGC142029; NSD 3; Nuclear set domain containing 3; Nuclear SET domain containing protein 3; pp14328; Whistle; WHSC1 like protein 1; WHSC1L1 protein; Wolf Hirschhorn syndrome candidate 1 like 1; protein whistle; OTTHUMP00000228478; OTTHUMP00000228479; OTTHUMP00000228480; OTTHUMP00000228487; WHSC1-like protein 1; nuclear SET domain-containing protein 3; WHSC1-like 1 isoform 9 with methyltransferase activity to lysi;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human WHSC1L1-3729H Recombinant Human WHSC1L1, GST-tagged E.coli GST N-term-300aa
Human WHSC1L1-186H Recombinant Human WHSC1L1 protein, GST-tagged E.coli GST
Human WHSC1L1-28412TH Recombinant Human WHSC1L1, His-tagged E.coli His
Human WHSC1L1-148H Recombinant Human WHSC1L1 Protein, GST-tagged E.coli GST 1021-1322
Human WHSC1L1-313HCL Recombinant Human WHSC1L1 293 Cell Lysate HEK293 N/A
Human WHSC1L1-314HCL Recombinant Human WHSC1L1 293 Cell Lysate HEK293 N/A
Human WHSC1L1-2631H Recombinant Human WHSC1L1 Protein (1-645 aa), His-tagged Yeast His 1-645 aa
Mouse WHSC1L1-18546M Recombinant Mouse WHSC1L1 Protein Mammalian Cell His
Mouse WHSC1L1-10178M Recombinant Mouse WHSC1L1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse WHSC1L1-10178M-B Recombinant Mouse WHSC1L1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

WHSC1L1 involved in several pathways and played different roles in them. We selected most pathways WHSC1L1 participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with WHSC1L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Lysine degradationSUV39H2;TMLHE;SETMAR;EHMT1B;ALDH1B1;MLL1;SETD1BA;ALDH7A1;PLOD2

WHSC1L1 has several biochemical functions, for example, histone methyltransferase activity (H3-K27 specific), histone methyltransferase activity (H3-K4 specific), histone-lysine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WHSC1L1 itself. We selected most functions WHSC1L1 had, and list some proteins which have the same functions with WHSC1L1. You can find most of the proteins on our site.

Function Related Protein
histone methyltransferase activity (H3-K27 specific)EHMT2;EZH2;EHMT1;WHSC1L1
histone methyltransferase activity (H3-K4 specific)WDR82;MLL1;SETD3;SETMAR;MLL5;SMYD1B;ASH1L;KMT2A;KMT2E
histone-lysine N-methyltransferase activitySMYD3;SUV39H1A;SUV39H1;SETD1BA;SETD8B;SUV39H1B;SETDB1B;SETD8A;EHMT2
protein bindingEFCAB4B;UBE2D3;APOA4;IL1R1;MCL1;KRTAP4-12;CDK16;SUMO3;MYBPHL
zinc ion bindingCSRP1A;FBXL19;ZNF385C;MMP8;MARCH2;RNFT2;ZDHHC3A;UMPS;PRICKLE1A

WHSC1L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WHSC1L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of WHSC1L1.

MLLT6; HEL25; RAD51; SLU7; HOXC4; MNDA; ATM; DAXX

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