Recombinant Human WHSC1L1, His-tagged

• Cat.No.: WHSC1L1-28412TH
• Product Overview: Recombinant fragment, corresponding to amino acids 240-645 of Human NSD3 with an N terminal His tag. 60 kDa; Predicted mwt: 47 kDa

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 240-645 a.a.
• Description: This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described.
• Conjugation: HIS
• Form: Lyophilised:Reconstitute with 106 μl distilled water.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: EEPVLKEEAPVQPILSSVPTTEVSTGVKFQVGDLVWSKVG TYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQP ERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQK IRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYI DKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQPEQT NAGEVASSLSSTEIRRHSQRRHTSAEEEEPPPVKIAWK TAAARKSLPASITMHKGSLDLQKCNMSPVVKIEQVFALQN ATGDGKFIDQFVYSTKGIGNKTEISVRGQDRLIISTPN QRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSES EKSTEVVPKKKIKKEQVETVPQATVKTGLQKGSADRGVQG SVRFSDSSVSAAIEETVD

Gene Information

• Gene Name: WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 [ Homo sapiens ]
• Official Symbol: WHSC1L1
• Synonyms: WHSC1L1; Wolf-Hirschhorn syndrome candidate 1-like 1; histone-lysine N-methyltransferase NSD3; FLJ20353; NSD3
• Gene ID: 54904
• mRNA Refseq: NM_017778
• Protein Refseq: NP_060248
• MIM: 607083
• Uniprot ID: Q9BZ95
• Chromosome Location: 8p11.2
• Pathway: Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem
• Function: histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity; transferase activity; zinc ion binding