Recombinant Human WHSC1L1 protein, GST-tagged

• Cat.No.: WHSC1L1-186H
• Product Overview: Recombinant Human WHSC1L1(a.a. 1021-1322) fused with GST tag at N-terminal was expressed in E. coli.

Specification

• Description: NSD3 is a histone methyltransferase that preferentially methylates Lys4 and Lys27 of histone H3. Lys4 methylation usually represents a specific tag for epigenetic transcriptional activation, while Lys27 is a mark for transcriptional repression.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 3 mM DTT and 20% glycerol.
• Molecular Mass: 61 kDa
• Purity: >96%
• Applications: Suitable for protein binding studies, as an immunogen, or as a Western blotting control.
• Storage: >6 months at -80 centigrade. Avoid freeze/thaw cycles.
• Concentration: 0.44 mg/ml

Gene Information

• Gene Name: WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 [ Homo sapiens ]
• Official Symbol: WHSC1L1
• Synonyms: WHSC1L1; Wolf-Hirschhorn syndrome candidate 1-like 1; histone-lysine N-methyltransferase NSD3; FLJ20353; NSD3; protein whistle; WHSC1-like protein 1; nuclear SET domain-containing protein 3; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; pp14328; MGC126766; MGC142029; DKFZp667H044
• Gene ID: 54904
• mRNA Refseq: NM_023034
• Protein Refseq: NP_075447
• MIM: 607083
• UniProt ID: Q9BZ95
• Chromosome Location: 8p11.2
• Pathway: Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem
• Function: histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity; transferase activity; zinc ion binding