WNT16 Protein, wingless-type MMTV integration site family, member 16


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Official Full Name wingless-type MMTV integration site family, member 16
Background The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5 termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. [provided by RefSeq, Jul 2008]
Synonyms WNT16; wingless-type MMTV integration site family, member 16; protein Wnt-16; wingless-type MMTV integration site family member 16b;
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • His
    • GST
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human WNT16-1477H Recombinant Human WNT16 protein, His & GST-tagged E.coli His/GST
    Human WNT16-243H Recombinant Human WNT16, StrepII-tagged Human Cell Strep II
    Human WNT16-299HCL Recombinant Human WNT16 293 Cell Lysate HEK293 N/A
    Human WNT16-300HCL Recombinant Human WNT16 293 Cell Lysate HEK293 N/A
    Zebrafish WNT16-5842Z Recombinant Zebrafish WNT16 Mammalian Cell His

    WNT16 involved in several pathways and played different roles in them. We selected most pathways WNT16 participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway TP53; CAMK2A; GSK3AA; WNT11B; WNT11R; PRKCBB; BAMBIA; CCND1; WNT5A; PRKCG
    Hedgehog signaling pathway PTCH1; WNT9A; DYRK1AA; PRKACAA; WNT4; WNT2B; CSNK1A1L; CSNK1G1; RAB23; CSNK1DA
    Hippo signaling pathway PARD6B; FZD1; APC2; WNT2; GDF5; GLI2; SMAD7; TGFB3; YAP1; CCND1
    Signaling pathways regulating pluripotency of stem cells POU5F1; LIF; JARID2; MAPK1; HESX1; FZD3; WNT4; FZD6; NANOG; WNT9B
    Melanogenesis WNT2B; GNAO1B; FZD8A; EDNRB2; CAMK2G; GNA15.1; CAMK2D1; KITLG; CREB1A; FZD2
    Pathways in cancer GNG11; NFKBIA; FZD5; WNT8B; RASSF1; AKT2; FGF7; BDKRB1; FZD1; BIRC5
    Transcriptional misregulation in cancer PML; SUPT3H; FCGR1; ERG; IL6; CCNT1; HIST1H3G; NTRK1; RXRB; H3F3B
    Proteoglycans in cancer CAV1; TGFB1; GPC3; PIK3CD; ACTB; PLCE1; SLC9A1; HCLS1; ARHGEF12; AKT2
    Basal cell carcinoma DVL2; BMP4; STK36; AXIN1; WNT3; SETD6; GLI2; WNT7B; FZD6; WNT10B

    WNT16 has several biochemical functions, for example, frizzled binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT16 itself. We selected most functions WNT16 had, and list some proteins which have the same functions with WNT16. You can find most of the proteins on our site.

    Function Related Protein
    frizzled binding WNT9A; CTHRC1; WNT4; NDP; WNT16; WNT11; RSPO3; WNT8B; WNT2B; FZD7

    WNT16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT16 here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT16.



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