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WNT16

  • Official Full Name

    wingless-type MMTV integration site family, member 16

  • Overview

    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5 termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. [provided by RefSeq, Jul 2008]
  • Synonyms

    WNT16; wingless-type MMTV integration site family, member 16; protein Wnt-16; wingless-type MMTV integration site family member 16b;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
  • GST
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human WNT16-243H Recombinant Human WNT16, StrepII-tagged Human Cell Strep II 30-365, 336 a.a.
Human WNT16-299HCL Recombinant Human WNT16 293 Cell Lysate HEK293 N/A
Human WNT16-300HCL Recombinant Human WNT16 293 Cell Lysate HEK293 N/A
Human WNT16-2057H Recombinant Human WNT16 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human WNT16-583H Recombinant Human WNT16 Protein, His-tagged E.coli N-His Asn30-Lys365
Human WNT16-1477H Recombinant Human WNT16 protein, His & GST-tagged E.coli His/GST Asn30~Lys365 (Accession # Q9UBV4)
Human WNT16-2359H-B Recombinant Human WNT16 Protein Pre-coupled Magnetic Beads HEK293
Human WNT16-114H Active Recombinant Human WNT16 Protein E. coli
Human WNT16-1825HFL Recombinant Full Length Human WNT16 Protein, C-Flag-tagged Mammalian cells Flag
Human WNT16-2359H Recombinant Human WNT16 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human WNT16-5899H Recombinant Human WNT16 Protein (Asn30-Lys365), N-GST tagged E.coli N-GST Asn30-Lys365
Mouse Wnt16-7005M Recombinant Mouse Wnt16 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish WNT16-5842Z Recombinant Zebrafish WNT16 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • WNT16 Related Research Area

WNT16 involved in several pathways and played different roles in them. We selected most pathways WNT16 participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayNFATC2;CUL1A;FBXW11A;MAP3K7;PPP3CCA;CCND2A;LRP6;FZD8;INVS
Hedgehog signaling pathwayPRKACG;WNT2BA;WNT11;PTCH1;WNT2;WNT10B;PRKACAA;WNT3;WNT4
Hippo signaling pathwayAREG;YWHAE;WNT2;SMAD1;AMH;GDF5;ITGB2;FBXW11;YWHAG
Signaling pathways regulating pluripotency of stem cellsREST;WNT1;FGFR2;BMP2;ZIC3;ESRRB;AKT2;DLX5;IGF1
MelanogenesisCAMK2A;CAMK2D;Adcy4;GNAQ;CAMK2D1;WNT2BA;PLCB1;PRKCG;ASIP
HTLV-I infectionXPO1;ANAPC2;CCNB2;CDC16;CDC20;SMAD2;AKT2;DVL2;BAX
Pathways in cancerTCF7L2;WNT8A;BID;APPL1;MMP2;FGF21;BRAF;HSP90AA1;VEGFC
Transcriptional misregulation in cancerNUPR1;MMP3;HIST2H3C1;Aff1;KDM6A;HIST1H3C;IL-8;Bcl2a1b;FCGR1A
Proteoglycans in cancerSTAT3;PIK3R5;WNT7A;FLNA;VAV2;PIK3R2;PAK1;TWIST1;ITGB5
Basal cell carcinomaBMP2;WNT2B;WNT5A;WNT8B;FZD7;FZD8;TP53;WNT9A;WNT8A

WNT16 has several biochemical functions, for example, frizzled binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT16 itself. We selected most functions WNT16 had, and list some proteins which have the same functions with WNT16. You can find most of the proteins on our site.

Function Related Protein
frizzled bindingWNT8B;WNT2;BAMBI;WNT2B;WNT4;WNT2BA;WNT8A;WNT11;WNT3A

WNT16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT16 here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT16.

BCL6

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