Recombinant Full Length Human WNT16 Protein, C-Flag-tagged

• Cat.No.: WNT16-1825HFL
• Product Overview: Recombinant Full Length Human WNT16 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 37.6 kDa
• AA Sequence: MDRAALLGLARLCALWAALLVLFPY GAQGNWMWLGIASFGVPEKLGCANL PLNSRQKELCKRKPYLLPSI REGARLGIQECGSQFRHERWNCMIT AAATTAPMGASPLFGYELSSGTKET AFIYAVMAAGLVHSVTRSCS AGNMTECSCDTTLQNGGSASEGWHW GGCSDDVQYGMWFSRKFLDFPIGNT TGKENKVLLAMNLHNNEAGR QAVAKLMSVDCRCHGVSGSCAVKTC WKTMSSFEKIGHLLKDKYENSIQIS DKTKRKMRRREKDQRKIPIH KDDLLYVNKSPNYCVEDKKLGIPGT QGRECNRTSEGADGCNLLCCGRGYN THVVRHVERCECKFIWCCYV RCRRCESMTDVHTCK TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway

Gene Information

• Gene Name: WNT16 Wnt family member 16 [ Homo sapiens (human) ]
• Official Symbol: WNT16
• Synonyms: wingless-related MMTV integration site 16; wingless-type MMTV integration site family, member 16
• Gene ID: 51384
• mRNA Refseq: NM_057168.2
• Protein Refseq: NP_476509.1
• MIM: 606267
• UniProt ID: Q9UBV4