XPO5 Protein, exportin 5

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XPO5

Official Full Name	exportin 5
Background	This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process.
Synonyms	XPO5; exportin 5; exportin-5; KIAA1291; Exp 5; Exp5; Exportin5; FLJ14239; FLJ32057; FLJ45606; OTTHUMP00000016472; Ran binding protein 21; Ran-binding protein 21; Ranbp 21; Ranbp21; Xpo 5; XPO5_HUMAN

Species :
Chicken
Human
Mouse
Rhesus Macaque

Source :
E.coli
HEK293
HEK293T
Mammalian Cell

Tag :
C-Myc/DDK
His
T7
Myc/DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag
Human	XPO5-1405H	Recombinant Human XPO5 protein, Myc/DDK-tagged	HEK293T	Myc/DDK
Human	XPO5-397H	Recombinant Human XPO5 Protein, MYC/DDK-tagged, C13 and N15-labeled	HEK293	C-Myc/DDK
Human	XPO5-1404H	Recombinant Human XPO5 protein, His & T7-tagged	E.coli	His/T7
Human	XPO5-1938HCL	Recombinant Human XPO5 cell lysate		N/A
Mouse	XPO5-18631M	Recombinant Mouse XPO5 Protein	Mammalian Cell	His
Rhesus Macaque	XPO5-5231R	Recombinant Rhesus monkey XPO5 Protein, His-tagged	Mammalian Cell	His
Chicken	XPO5-5030C	Recombinant Chicken XPO5	Mammalian Cell	His

Involved Pathway Protein Function Interacting Protein XPO5 Related Articles

XPO5 involved in several pathways and played different roles in them. We selected most pathways XPO5 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with XPO5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RNA transport	ELAC2; EIF2S2; UPF3A; MAGOH2; POP5; EIF4EBP3L; EIF3JA; EIF4EBP2; EIF1B; NUP98

XPO5 has several biochemical functions, for example, RNA binding, Ran GTPase binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by XPO5 itself. We selected most functions XPO5 had, and list some proteins which have the same functions with XPO5. You can find most of the proteins on our site.

Function	Related Protein
RNA binding	PABPC1L; KHDRBS1A; PES; FXR1; EIF2S1A; FAU; UPF3A; RBM20; SNRPA; EIF4G1A
Ran GTPase binding	IPO9; RANBP2; IPO8; DPY19L2; XPO4; XPO6; IPO5; NUP153; XPO5; CSE1L
mRNA binding	NOVA1; LUC7L3; KIAA0020; CELF1; RBPMS2B; PURB; DHFR; RPL35; EIF4A1; CELF3
poly(A) RNA binding	UBE2I; PRPF4B; ACAA2; CCBL2; SFPQ; CCDC9; RRP7A; RBMS1; DIMT1L; CDK11B
pre-miRNA binding	TARBP2; DICER1; XPO5
contributes_to pre-miRNA binding	RAN; TARBP2; DICER1; XPO5
protein binding	LAX1; SCYL2; ITGAL; SUFU; PRKAR2AA; SSX3; PCBD2; CTH; MUTED; ARF5
protein transporter activity	AP1S3; KPNA3; RANBP6; IPO11; TNPO2; PGAP2; RAMP3; VPS26B; AP1S3A; CCT6B
tRNA binding	MADD; TRMT1; TRNT1; YARS2; FARSA; AIMP1; MARS; TRMT11; NSUN2; AARS2

XPO5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XPO5 here. Most of them are supplied by our site. Hope this information will be useful for your research of XPO5.

pre-let-7a-1; MYC; vpu; Dlg4; PTP4A3; TNFRSF1B; MAGEA6; ARF6; RAN; CCNA1; FADD; SERINC3; IKBKE; TSC22D1; NEK6

Khacho, M; Mekhail, K; et al. eEF1A Is a Novel Component of the Mammalian Nuclear Protein Export Machinery. MOLECULAR BIOLOGY OF THE CELL 19:5296-5308(2008).

Kurihara, Y; Kawamura, Y; et al. Maintenance of genomic methylation patterns during preimplantation development require's the somatic form of DNA methyltransferase 1. DEVELOPMENTAL BIOLOGY 313:335-346(2008).

XPO5

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XPO5

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