XPO5 Protein, exportin 5

XPO5

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XPO5

Official Full Name exportin 5
Background This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process.
Synonyms XPO5; exportin 5; exportin-5; KIAA1291; Exp 5; Exp5; Exportin5; FLJ14239; FLJ32057; FLJ45606; OTTHUMP00000016472; Ran binding protein 21; Ran-binding protein 21; Ranbp 21; Ranbp21; Xpo 5; XPO5_HUMAN
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • C-Myc/DDK
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human XPO5-1405H Recombinant Human XPO5 protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human XPO5-397H Recombinant Human XPO5 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human XPO5-1404H Recombinant Human XPO5 protein, His & T7-tagged E.coli His/T7
    Human XPO5-1938HCL Recombinant Human XPO5 cell lysate N/A
    Mouse XPO5-18631M Recombinant Mouse XPO5 Protein Mammalian Cell His
    Rhesus Macaque XPO5-5231R Recombinant Rhesus monkey XPO5 Protein, His-tagged Mammalian Cell His
    Chicken XPO5-5030C Recombinant Chicken XPO5 Mammalian Cell His

    XPO5 involved in several pathways and played different roles in them. We selected most pathways XPO5 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with XPO5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport ELAC2; EIF2S2; UPF3A; MAGOH2; POP5; EIF4EBP3L; EIF3JA; EIF4EBP2; EIF1B; NUP98

    XPO5 has several biochemical functions, for example, RNA binding, Ran GTPase binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by XPO5 itself. We selected most functions XPO5 had, and list some proteins which have the same functions with XPO5. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding PABPC1L; KHDRBS1A; PES; FXR1; EIF2S1A; FAU; UPF3A; RBM20; SNRPA; EIF4G1A
    Ran GTPase binding IPO9; RANBP2; IPO8; DPY19L2; XPO4; XPO6; IPO5; NUP153; XPO5; CSE1L
    mRNA binding NOVA1; LUC7L3; KIAA0020; CELF1; RBPMS2B; PURB; DHFR; RPL35; EIF4A1; CELF3
    poly(A) RNA binding UBE2I; PRPF4B; ACAA2; CCBL2; SFPQ; CCDC9; RRP7A; RBMS1; DIMT1L; CDK11B
    pre-miRNA binding TARBP2; DICER1; XPO5
    contributes_to pre-miRNA binding RAN; TARBP2; DICER1; XPO5
    protein binding LAX1; SCYL2; ITGAL; SUFU; PRKAR2AA; SSX3; PCBD2; CTH; MUTED; ARF5
    protein transporter activity AP1S3; KPNA3; RANBP6; IPO11; TNPO2; PGAP2; RAMP3; VPS26B; AP1S3A; CCT6B
    tRNA binding MADD; TRMT1; TRNT1; YARS2; FARSA; AIMP1; MARS; TRMT11; NSUN2; AARS2

    XPO5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XPO5 here. Most of them are supplied by our site. Hope this information will be useful for your research of XPO5.

    pre-let-7a-1; MYC; vpu; Dlg4; PTP4A3; TNFRSF1B; MAGEA6; ARF6; RAN; CCNA1; FADD; SERINC3; IKBKE; TSC22D1; NEK6

    Khacho, M; Mekhail, K; et al. eEF1A Is a Novel Component of the Mammalian Nuclear Protein Export Machinery. MOLECULAR BIOLOGY OF THE CELL 19:5296-5308(2008).
    Kurihara, Y; Kawamura, Y; et al. Maintenance of genomic methylation patterns during preimplantation development require's the somatic form of DNA methyltransferase 1. DEVELOPMENTAL BIOLOGY 313:335-346(2008).

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