ZWINT Protein, ZW10 interactor


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Official Full Name ZW10 interactor
Background This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms ZWINT; ZW10 interactor; KNTC2AP; HZwint1; KNTC 2 AP; MGC 117174; MGC117174; ZW10 interacting protein 1; ZWINT 1; zwint-1; OTTHUMP00000019626; OTTHUMP00000019628; ZW10-interacting protein 1; human ZW10 interacting protein-1; ZWINT1; HZwint-1
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ZWINT-153H Recombinant Human ZWINT, His-tagged E.coli His
    Human ZWINT-3887H Recombinant Human ZWINT, GST-tagged E.coli GST
    Human ZWINT-458H Recombinant Human ZWINT Protein, His-tagged E.coli His
    Human ZWINT-9179HCL Recombinant Human ZWINT 293 Cell Lysate HEK293 N/A
    Mouse ZWINT-19258M Recombinant Mouse ZWINT Protein Mammalian Cell His
    Rat ZWINT-6721R Recombinant Rat ZWINT Protein Mammalian Cell His

    ZWINT involved in several pathways and played different roles in them. We selected most pathways ZWINT participated on our site, such as Cell Cycle, Mitotic, M Phase, Mitotic Anaphase, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZWINT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell Cycle, Mitotic CEP78; CENPQ; LIN52; CEP72; CDKN2C; FGFR1OP; NCAPD2; CEP70; SPC25; NUDC
    Mitotic Anaphase CDCA5; CENPO; SGOL1; TMPO; PANE1; CENPN; NDC80; RCC2; ITGB3BP; B9D2
    Mitotic Metaphase and Anaphase MIS12; NDEL1B; CENPL; ITGB3BP; SPC25; CENPQ; CCDC99; CDCA5; PMF1; CENPE
    Mitotic Prometaphase CENPC1; CDCA5; CENPH; SPDL1; NUF2; SMC2; PDS5A; PMF1; SKA1; SPC25
    RHO GTPases Activate Formins SKA2; DIAPH1; ZWILCH; DSN1; SPDL1; CLIP1; RCC2; RANGAP1B; NDEL1A; NUF2

    ZWINT has several biochemical functions, for example, protein N-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZWINT itself. We selected most functions ZWINT had, and list some proteins which have the same functions with ZWINT. You can find most of the proteins on our site.

    Function Related Protein
    protein N-terminus binding EIF3E; STX5; GLRX; NIPBL; SCT; EIF5A; ID1; ACTN4; ARF6; TRP53
    protein binding UCHL1; BLK; MDFIC; SULT1E1; UBE4A; EMP1; ATF4; DVL1; STBD1; ATXN7L3

    ZWINT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZWINT here. Most of them are supplied by our site. Hope this information will be useful for your research of ZWINT.

    NDC80; BECN1; MIS12

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