A4GNT

  • Official Full Name

    alpha-1,4-N-acetylglucosaminyltransferase

  • Overview

    This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane.
  • Synonyms

    A4GNT; alpha-1,4-N-acetylglucosaminyltransferase; alpha4GnT; MGC149493;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human A4GNT-16H Recombinant Human A4GNT, His-tagged HEK293 His
Human A4GNT-17H Recombinant Human A4GNT, His-DHFR-tagged E.coli His/DHFR
Human A4GNT-9162HCL Recombinant Human A4GNT 293 Cell Lysate HEK293 N/A
Human A4GNT-2462H Recombinant Human A4GNT protein, His-tagged E.coli His 76-340 aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • A4GNT Related Articles
  • A4GNT Related Research Area

A4GNT involved in several pathways and played different roles in them. We selected most pathways A4GNT participated on our site, such as Metabolism of proteins, O-linked glycosylation, O-linked glycosylation of mucins, which may be useful for your reference. Also, other proteins which involved in the same pathway with A4GNT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolism of proteinsIGFBP2;GALNTL5;TRAPPC5;DPH5;MPDU1B;TTR;PROZ;FKBP14;TOMM6
O-linked glycosylationADAMTSL4;THSD7A;GALNT5;GALNTL2;ADAMTS15;ADAMTS3;GALNT13;ADAMTS4;SSPO
O-linked glycosylation of mucinsMUC1;GALNT13;KCNA6;B3GNT6;GALNT5;GALNTL5;MUC4;B3GNT2A;GALNTL2
Post-translational protein modificationRING1;KCNA6;YKT6;GCNT3;MUC4;NANP;PIGK;ADAMTS10;STT3A
heparan sulfate biosynthesisHS3ST4;MAPK1IP1L;A4GNT
heparan sulfate biosynthesis (late stages)HS3ST4;A4GNT

A4GNT has several biochemical functions, for example, acetylglucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by A4GNT itself. We selected most functions A4GNT had, and list some proteins which have the same functions with A4GNT. You can find most of the proteins on our site.

Function Related Protein
acetylglucosaminyltransferase activityB3GNT9-PS;DPY19L4;GALNTL4;C3orf39;MGAT1A;GALNT18A;B3GNT8;XYLT2;OGT

A4GNT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with A4GNT here. Most of them are supplied by our site. Hope this information will be useful for your research of A4GNT.

Karasawa, F; Shiota, A; et al. Essential role of gastric gland mucin in preventing gastric cancer in mice. JOURNAL OF CLINICAL INVESTIGATION 122:923-934(2012).
Nakayama, J; Katsuyama, T; et al. Recent progress in paradoxical concanavalin A staining. ACTA HISTOCHEMICA ET CYTOCHEMICA 33:153-157(2000).
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