ABCA4

  • Official Full Name

    ATP-binding cassette, sub-family A (ABC1), member 4
  • Overview

    ATP-binding cassette, sub-family A (ABC1), member 4, also known as ABCA4 or ABCR, is a protein which in humans is encoded by the ABCA4 gene.
  • Synonyms

    FFM;RMP;ABCR;RP19;STGD;ABC10;ARMD2;CORD3;STGD1;FLJ17534;DKFZp781N1972;retinal-specific ATP-binding cassette transporter
Cat.# Product name Source (Host) Species Tag Protein Length Price
ABCA4-033H Recombinant Human ABCA4 Protein, GST-Tagged Wheat Germ Human GST
ABCA4-1080M Recombinant Mouse ABCA4 Protein Mammalian Cells Mouse His
ABCA4-8115H Recombinant Human ABCA4 protein, His & T7-tagged E.coli Human His&T7 Gly1398~Asn1727
ABCA4-0607H Recombinant Human ABCA4 Protein (Gly1398-Asn1727), N-His-tagged E.coli Human His Gly1398-Asn1727
ABCA4-182M Recombinant Mouse ABCA4 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ABCA4-182M-B Recombinant Mouse ABCA4 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ABCA4 involved in several pathways and played different roles in them. We selected most pathways ABCA4 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ABC transporters SUR2A,ABCB9,ABCB6A,ABCB1,ABCG1,ABCB11,ABCC1,ABCG2,ABCG2A,ABCA5

    Protein Function

    ABCA4 has several biochemical functions, for example, ATP binding,ATPase activity,ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCA4 itself. We selected most functions ABCA4 had, and list some proteins which have the same functions with ABCA4. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ATP8B3,SGK2A,MYO7B,ATP2A3,ROCK1,PDS5B,ATP2A2,PLK3,PRPS1L1,EPHB2B
    transporter activity RBP7,SLC22A1,AQP8A.1,SLC51A,PPIAL4A,CRABP1B,PMP2,MIPB,APODB,SLC23A1
    nucleotide binding P2RX4A,TIAL1,RBM39B,RAB32A,UBE1Y1,RAB1BB,OASL2,CPSF7,RBPMS2A,SMC2
    ATPase activity ABCF3,KIF4A,ABCG3,ERCC3,KIF3C,PSMC2,ATP13A,DQX1,KIF27,MLH3
    cholesterol transporter activity APOA4B.2,APOA1A,APOEB,APOA1,ABCA7,ABCG1,APOB,ABCA1B,ABCA4A,ABCA13
    phospholipid-translocating ATPase activity ATP8B3,Atp8a2,ATP9A,ATP8B1,ATP10A,ATP9B,ATP8A1,ATP11A,ATP8B5,ATP11C
    ATPase activity, coupled to transmembrane movement of substances DPY19L2,ABCA9,IPO8,Abcb1b,ABCD3A,ABCA6,ABCB6A,ABCA13,ABCA1,ABCA5
    phospholipid transporter activity MTTP,CETP,OSBPL8,ABCA4A,MFSD2AA,ABCA13,ATP8B5,APOA1,ABCA1,GLTPD1

    Interacting Protein

    ABCA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCA4.

    Resources

    References

    • Grassmann, F; Bergholz, R; et al. Common synonymous variants in ABCA4 are protective for chloroquine induced maculopathy (toxic maculopathy). BMC OPHTHALMOLOGY 15:-(2015).
    • Puntel, A; Maeda, A; et al. Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles. BIOMATERIALS 44:103-110(2015).

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