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Official Full Name ATP-binding cassette, sub-family C (CFTR/MRP), member 11
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.
Synonyms ABCC11; ATP-binding cassette, sub-family C (CFTR/MRP), member 11; ATP-binding cassette sub-family C member 11; MRP8; ABCC 11; ATP binding cassette protein C11; ATP binding cassette sub family C (CFTR/MRP) member 11; ATP binding cassette sub family C member 11; ATP binding cassette transporter MRP8; ATP binding cassette transporter sub family C member 11; EWWD; Multi resistance protein 8; Multidrug resistance associated protein 8; OTTHUMP00000164191; WW; OTTHUMP00000164192; multi-resistance protein 8; ATP-binding cassette protein C11; ATP-binding cassette transporter MRP8; multidrug resistance-associated protein 8; ATP-binding cassette transporter
    • Species :
    • Human
    • Source :
    • E.coli
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ABCC11-044H Recombinant Human ABCC11 Protein, GST-Tagged Wheat Germ GST
    Human ABCC11-045H Recombinant Human ABCC11 Protein, GST-Tagged Wheat Germ GST
    Human ABCC11-5HCL Recombinant Human ABCC11 cell lysate N/A
    Human ABCC11-8123H Recombinant Human ABCC11 protein, His & T7-tagged E.coli His/T7

    ABCC11 involved in several pathways and played different roles in them. We selected most pathways ABCC11 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCC11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ABC transporters ABCA4; ABCB6; ABCA7; ABCA1; ABCC6; ABCA13; SUR2A; ABCB3L1; ABCB11; ABCG2

    ABCC11 has several biochemical functions, for example, ATP binding, ATPase activity, coupled to transmembrane movement of substances, organic anion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCC11 itself. We selected most functions ABCC11 had, and list some proteins which have the same functions with ABCC11. You can find most of the proteins on our site.

    Function Related Protein
    ATPase activity, coupled to transmembrane movement of substances ABCD4; ABCB1A; ABCC5; ABCA7; ABCA13; ABCG2A; ABCA4; ABCD3; Abcb1b; ABCB4
    organic anion transmembrane transporter activity SLC22A20; SLC22A7B.1; ABCC11; SLCO1A4; SLCO1B3; SLC17A3; SLCO3A1; SLCO1A2; SLCO4C1; ABCC2
    purine nucleotide transmembrane transporter activity ABCC11

    ABCC11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCC11 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCC11.

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