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Official Full Name ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Background The protein encoded by the SUR1 gene is a member of the superfamily of ATP-binding cassette . No disease has been associated with this gene thus far.
Synonyms ABCC8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; sulfonylurea receptor; Sur; SUR1; D930031B21Rik
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ABCC8-301376H Recombinant Human ABCC8 protein, GST-tagged E.coli GST
    Human ABCC8-053H Recombinant Human ABCC8 Protein, GST-Tagged Wheat Germ GST
    Human ABCC8-238H Recombinant Human ABCC8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ABCC8-5866H Recombinant Human ABCC8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ABCC8-8122H Recombinant Human ABCC8 protein, His & T7-tagged E.coli His/T7
    Mouse Abcc8-1460M Recombinant Mouse Abcc8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat ABCC8-408R Recombinant Rat ABCC8 Protein Mammalian Cell His
    Zebrafish ABCC8-7696Z Recombinant Zebrafish ABCC8 Mammalian Cell His

    ABCC8 involved in several pathways and played different roles in them. We selected most pathways ABCC8 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCC8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ABC transporters ABCD2; ABCC5; ABCB9; ABCA1; ABCC9; ABCB4; ABCB10; ABCD3A; TAP1; ABCA6

    ABCC8 has several biochemical functions, for example, ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCC8 itself. We selected most functions ABCC8 had, and list some proteins which have the same functions with ABCC8. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding KIAA1804; STK10; CDK14; ROR2; ABCA3; RTCD1; PGK1; CDK5; MAP3K3; EPHA2
    ATPase activity PMS1; MYO19; KIFC3; KIF25; ATAD1B; EIF4A1B; ABCA1B; KIFC2; KIF6; KIF2B
    ATPase activity, coupled to transmembrane movement of substances ABCD3B; ABCB7; ABCC6; ABCG8; ABCG3; ABCC3; ATP6V1D; ABCD1; ABCC10; ABCG2D
    nucleotide binding MOV10B.1; RBM15; NXF3; LTK; EPHB4B; HNRNPA0B; HIPK3A; BMPR1BB; RAB12; RBM17
    sulfonylurea receptor activity ABCC8; ABCC9

    ABCC8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCC8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCC8.

    Alves, C; Constanca, J; et al. A novel atypical presentation of insulin autoimmune syndrome (Hirata's disease) in a child. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 26:1163-1166(2013).
    Irgens, HU; Molnes, J; et al. Prevalence of monogenic diabetes in the population-based Norwegian Childhood Diabetes Registry. DIABETOLOGIA 56:1512-1519(2013).

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