Home / Products / ADAMTS3


Official Full Name ADAM metallopeptidase with thrombospondin type 1 motif, 3
Background This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues. [provided by RefSeq, Jul 2008]
Synonyms ADAMTS3; ADAM metallopeptidase with thrombospondin type 1 motif, 3; ADAMTS-4; A disintegrin and metalloproteinase with thrombospondin motifs 3; ADAM-TS3; ADAMTS-3; PC II-NP; ADAM-TS 3; zinc metalloendopeptidase; procollagen II N-proteinase; procollagen II amino propeptide-processing enzyme; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3;
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADAMTS3-1965H Recombinant Human ADAMTS3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ADAMTS3-3015H Recombinant Human ADAMTS3, His-tagged E.Coli or Yeast His
    Human ADAMTS3-305H Recombinant Human ADAMTS3 Protein, GST-tagged Wheat Germ GST
    Human ADAMTS3-736H Recombinant Human ADAMTS3 Mammalian Cell His
    Human ADAMTS3-9030HCL Recombinant Human ADAMTS3 293 Cell Lysate HEK293 N/A
    Human ADAMTS3-9389H Recombinant Human ADAMTS3, His-tagged E.coli His
    Mouse Adamts3-1529M Recombinant Mouse Adamts3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Zebrafish ADAMTS3-8392Z Recombinant Zebrafish ADAMTS3 Mammalian Cell His

    ADAMTS3 involved in several pathways and played different roles in them. We selected most pathways ADAMTS3 participated on our site, such as Collagen biosynthesis and modifying enzymes, Collagen formation, Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Collagen biosynthesis and modifying enzymes COL6A1; COL8A1A; COL4A6; COL5A1; COL23A1; COL5A3B; EMID2; COL9A1A; ADAMTS3; COL28A1
    Extracellular matrix organization COL9A1; CTSLL; ADAM15; PPIB; ELANE; SPARC; DAG1; ICAM4; COL6A2; LAMB1B
    Metabolism of proteins ATP6AP2; PAPPAB; ADAMTSL4; MUCL1; TRAPPC2; MPDU1; SFTPB; CTAGE5; SPON2; GATA6
    O-glycosylation of TSR domain-containing proteins ADAMTSL5; ADAMTS5; ADAMTS15; ADAMTS8; ADAMTS13; THSD1; SPON1A; ADAMTS1; ADAMTS4; ADAMTSL3
    O-linked glycosylation ADAMTSL1; SPON2; GALNTL5; ADAMTS10; ADAMTS1; SPON1; GALNT13; ST6GALNAC2; MUC12; MUC5AC
    Post-translational protein modification ST6GALNAC1.2; ADAMTS3; TRAPPC2; ADAMTS1; ADAMTSL1; NAPG; SEC22A; THSD7A; DHPS; MUC13

    ADAMTS3 has several biochemical functions, for example, endopeptidase activity, heparin binding, metalloendopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTS3 itself. We selected most functions ADAMTS3 had, and list some proteins which have the same functions with ADAMTS3. You can find most of the proteins on our site.

    Function Related Protein
    endopeptidase activity SENP3; SENP5; PCSK6; SENP3A; PSMB8F; ACE; TRAPPC12; ADAM10; KLK1B16; TMEM59
    heparin binding SLIT1; CCL15; NOV; SELP; RSPO3; FSTL1; GM4980; AAMP; FMODA; CCL8
    metalloendopeptidase activity MMP25; MBTPS2; PAPLN; ADAMTS9; ADAMTS16; MEP1A.1; ADAM28; MMP15; ADAMTS18; THOP1
    protein binding BAX; TRPC1; BMI1; PLCG1; SSR1; DNMT3B; Fgf15; ITGB1BP2; ALX1; UQCRH
    zinc ion binding PPARDB; FUS; DTX1; RNF6; IGHMBP2; SMAD3; ZFAND2B; NR2F2; ZFAND1; RFPL1

    ADAMTS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTS3.

    Pyun, JA; Kim, S; et al. Genome-wide association studies and epistasis analyses of candidate genes related to age at menarche and age at natural menopause in a Korean population. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY 21:522-529(2014).
    Chaemsaithong, P; Madan, I; et al. Characterization of the myometrial transcriptome in women with an arrest of dilatation during labor. JOURNAL OF PERINATAL MEDICINE 41:665-681(2013).

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy