Recombinant Human ADAMTS3 Protein, Flag-tagged

• Cat.No.: ADAMTS3-02H
• Product Overview: Recombinant protein from the full-length sequence of Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif 3 (ADAMTS3) (NM_014243), with a DYKDDDDK tag was expressed in human cells.

Specification

• Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage.
• Source: Human cells
• Species: Human
• Tag: Flag
• Molecular Mass: 135.4 kDa
• Endotoxin: < 0.1 ng/μg of protein (<1 EU/μg)
• Purity: > 90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
• Storage Buffer: Purified protein formulated in a sterile solution of TBS buffer, pH 7.4, without any preservatives

Gene Information

• Gene Name: ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 [ Homo sapiens (human) ]
• Official Symbol: ADAMTS3
• Synonyms: ADAMTS3; ADAM metallopeptidase with thrombospondin type 1 motif 3; HKLLS3; ADAMTS-4; A disintegrin and metalloproteinase with thrombospondin motifs 3; ADAM-TS 3; ADAM-TS3; ADAMTS-3; PC II-NP; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; procollagen II N-proteinase; procollagen II amino propeptide-processing enzyme; zinc metalloendopeptidase; EC 3.4.24.-
• Gene ID: 9508
• mRNA Refseq: NM_014243
• Protein Refseq: NP_055058
• MIM: 605011
• UniProt ID: O15072