AFF2

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AFF2

Official Full Name AF4/FMR2 family, member 2
Background This gene encodes a putative transcriptional activator that is a member of the AF4\FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.
Synonyms AFF2; AF4/FMR2 family, member 2; FMR2, fragile X mental retardation 2; AF4/FMR2 family member 2; FRAXE; AFF2_HUMAN; FMR2; FMR2P; Fragile X E mental retardation syndrome protein; fragile X mental retardation 2; Fragile X mental retardation 2 protein; fragile X mental retardation gene associated with FRAXE; mild or borderline mental retardation; MRX2; OTTHUMP00000024204; OX19; Protein FMR-2; Protein Ox19
    • Species :
    • Human
    • Mouse
    • Source :
    • E.Coli or Yeast
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AFF2-26444TH Recombinant Human AFF2 Wheat Germ N/A
    Human AFF2-406H Recombinant Human AFF2 Protein, GST-tagged Wheat Germ GST
    Mouse AFF2-1399M Recombinant Mouse AFF2 Protein Mammalian Cell His
    Mouse Aff2-3231M Recombinant Mouse Aff2, His-tagged E.Coli or Yeast His

    AFF2 involved in several pathways and played different roles in them. We selected most pathways AFF2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AFF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    AFF2 has several biochemical functions, for example, G-quadruplex RNA binding, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AFF2 itself. We selected most functions AFF2 had, and list some proteins which have the same functions with AFF2. You can find most of the proteins on our site.

    Function Related Protein
    G-quadruplex RNA binding PATL2; DHX36; Aff2; FXR1
    RNA binding RPL18; IREB2; PES; UBR5; RDM1; SFSWAP; CSTF1; CLUHA; NHP2L1A; WT1

    AFF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AFF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AFF2.

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