Recombinant Human AFF2 Protein, GST-tagged

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Recombinant Human AFF2 Protein, GST-tagged

AFF2 Related Products

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Cat.No. : AFF2-406H
Product Overview : Human AFF2 partial ORF ( NP_002016.1, 109 a.a. - 219 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a putative transcriptional activator that is a member of the AF4\FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. In addition, this gene contains 6-25 GCC repeats that are expanded to >200 repeats in the disease state. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jul 2016]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 37.95 kDa
AA Sequence : KNEPSFFPEQ KNRIIPPHQD NTHPSAPMPP PSVVILNSTL IHSNRKSKPE WSRDSHNPST VLASQASGQP NKMQTLTQDQ SQAKLEDFFV YPAEQPQIGE VEESNPSAKE D
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : AFF2 AF4/FMR2 family, member 2 [ Homo sapiens ]
Official Symbol : AFF2
Synonyms : AFF2; AF4/FMR2 family, member 2; FMR2, fragile X mental retardation 2; AF4/FMR2 family member 2; FRAXE; protein FMR-2; fragile X mental retardation 2 protein; fragile X E mental retardation syndrome protein; FMR2; MRX2; OX19; FMR2P;
Gene ID : 2334
mRNA Refseq : NM_001169122
Protein Refseq : NP_001162593
MIM : 300806
UniProt ID : P51816
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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