AGPAT2
-
Official Full Name
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
-
Overview
1-acyl-sn-glycerol-3-phosphate acyltransferase beta is an enzyme that in humans is encoded by the AGPAT2 gene. -
Synonyms
AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta); 1-acyl-sn-glycerol-3-phosphate acyltransferase beta; 1 acyl sn glycerol 3 phosphate acyltransferase beta; 1 acylglycerol 3 phosphate O acyltransferase 2; 1 AGP acyltransferase 2; 1 AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase 2; 1-AGP acyltransferase 2; 1-AGPAT 2; Berardinelli Seip congenital lipodystrophy; BSCL; BSCL1; EC 2.3.1.51; LPAAB; LPAAT beta; LPAAT-beta; Lysophosphatidic acid acyltransferase beta; Lysophosphatidic acid acyltransferase-beta; PLCB_HUMAN; AV000834; 2510002J07Rik;
- Recombinant Proteins
- Cell & Tissue Lysates
- Homo sapiens (Human)
- Human
- Mus musculus (Mouse)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | AGPAT2-428H | Recombinant Human AGPAT2 Protein, GST-tagged | Wheat Germ | GST | ||
Human | AGPAT2-429H | Recombinant Human AGPAT2 Protein, GST-tagged | Wheat Germ | GST | ||
Human | AGPAT2-8977HCL | Recombinant Human AGPAT2 293 Cell Lysate | HEK293 | N/A | ||
Human | AGPAT2-3573H | Recombinant Human AGPAT2 protein, His-tagged | E.coli | His | ||
Human | AGPAT2-930HF | Recombinant Full Length Human AGPAT2 Protein, GST-tagged | In Vitro Cell Free System | GST | 278 amino acids | |
Homo sapiens (Human) | RFL-20562HF | Recombinant Full Length Human 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Beta(Agpat2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (24-278) | |
Mus musculus (Mouse) | RFL25135MF | Recombinant Full Length Mouse 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Beta(Agpat2) Protein, His-Tagged | E.coli expression system | His | Full Length (1-278) | |
Zebrafish | AGPAT2-4827Z | Recombinant Zebrafish AGPAT2 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- AGPAT2 Related Articles
AGPAT2 involved in several pathways and played different roles in them. We selected most pathways AGPAT2 participated on our site, such as Adipogenesis, CDP-diacylglycerol biosynthesis, CDP-diacylglycerol biosynthesis I, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGPAT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Adipogenesis | CELF1;MBNL1;HMGA1;PLIN2;CEBPA;GATA2;NCOA2;FRZB;CREB1 |
CDP-diacylglycerol biosynthesis | GK5;CDS1;AGPAT2;AGPAT1;AGPAT6;GPAT2 |
CDP-diacylglycerol biosynthesis I | AGPAT2;AGPAT1 |
Fat digestion and absorption | MOGAT2;ABCG8;SLC27A4;PLA2G10;SCARB1;ACAT2;APOB;PPAP2B;Cel |
Fatty acid, triacylglycerol, and ketone body metabolism | HELZ2;ACOT8;ANKRD1;CPT1B;AGPAT2;MED16;CCNC;MED25;ABCA1 |
Glycerolipid metabolism | DGKD;TAE1;DGAT1;GLA;LPIN1;AKR1B1;LPIN3;PNPLA2;DGAT2 |
Glycerophospholipid biosynthesis | CEPT1A;PLD6;PTPMT1;CPNE7;PLBD1;ABHD4;ABHD3;MGLL;CPNE3 |
Glycerophospholipid metabolism | AGPAT1;CHPT1;PPAP2B;ACHE;LPCAT3;PLA2G12B;LPCAT1;LPIN1;PLA2G2A |
AGPAT2 has several biochemical functions, for example, 1-acylglycerol-3-phosphate O-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AGPAT2 itself. We selected most functions AGPAT2 had, and list some proteins which have the same functions with AGPAT2. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
1-acylglycerol-3-phosphate O-acyltransferase activity | AGPAT2;LPCAT2;ABHD5;AGPAT9L;LYCAT;AGPAT9;AGPAT3;LCLAT1;AGPAT4 |
AGPAT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGPAT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGPAT2.
ANKRD28; GMPS; ABCG8; PHRF1; SLC23A2; PHF11
- Q&As
- Reviews
Q&As (21)
Ask a questionResearch investigates AGPAT2’s impact on lipid droplet dynamics and accumulation.
Yes, AGPAT2’s function can impact brain lipid composition and neurological functions.
AGPAT2 contributes to phospholipid biosynthesis and remodeling pathways.
Mutations in AGPAT2 can cause lipodystrophy, leading to abnormal fat tissue distribution.
AGPAT2 adds fatty acids to glycerol-3-phosphate, forming lysophosphatidic acid (LPA).
Yes, AGPAT2 mutations can result in metabolic disorders and lipodystrophic phenotypes.
Yes, AGPAT2’s activity might impact inflammation through lipid metabolism pathways.
AGPAT2’s function can be involved in hepatic lipid accumulation and fatty liver disease.
Research explores AGPAT2’s role in metabolic disorders like obesity, diabetes, and lipodystrophy.
AGPAT2 catalyzes the acylation of glycerol-3-phosphate, a crucial step in phospholipid synthesis.
Research explores AGPAT2’s contribution to triglyceride synthesis and energy storage.
AGPAT2’s activity influences the lipid composition of various tissues.
Research explores AGPAT2’s role in de novo lipogenesis and fatty acid synthesis.
Yes, AGPAT2 is crucial for lipid metabolism and the synthesis of cellular membranes.
Yes, AGPAT2 is a potential target for modulating lipid metabolism and related diseases.
Yes, AGPAT2’s involvement in lipid synthesis can influence membrane fusion and trafficking.
AGPAT2 is primarily located in the endoplasmic reticulum (ER) membrane.
Research investigates AGPAT2’s role in lipid biosynthesis pathways.
Yes, AGPAT2’s function is essential for maintaining the composition and integrity of cellular membranes.
Yes, AGPAT2’s activity is linked to adipocyte differentiation and fat tissue development.
AGPAT2 contains transmembrane domains that allow it to function within membranes.
Customer Reviews (5)
Write a reviewThe product’s quality was evident in the absence of background interference in our assays.
The product’s cost-effectiveness and clear instructions were valuable in our experiments.
The benefits reaped from the product justified its price in terms of scientific progress.
Consistent outcomes bolstered the reliability of our conclusions, thanks to the product’s performance.
Clear, distinct gel bands in electrophoresis highlighted the product’s pure form.
Ask a Question for All AGPAT2 Products
Required fields are marked with *
My Review for All AGPAT2 Products
Required fields are marked with *