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Recombinant Human AK4, His-tagged

Cat.No. : AK4-3448H
Product Overview : Recombinant human AK4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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  • Gene Information
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Cat. No. : AK4-3448H
Description : AK4(adenylate kinase 4) is a member of the adenylate kinase family of enzymes. This protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Inherited mutations leading to AK4 deficiencies in erythrocytes have been implicated in hemolytic anemia.
Form : Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
Molecular Weight : 27.4 kDa (243aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
Purity : > 90 % by SDS - PAGE
Concentration : 1 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MASKLLRAVI LGPPGSGKGT VCQRIAQNFG LQHLSSGHFL RENIKASTEV GEMAKQYIEK SLLVPDHVIT RLMMSELENR RGQHWLLDGF PRTLGQAEAL DKICEVDLVI SLNIPFETLK DRLSRRWIHP PSGRVYNLDF NPPHVHGIDD VTGEPLVQQE DDKPEAVAAR LRQYKDVAKP VIELYKSRGV LHQFSGTETN KIWPYVYTLF SNKITPIQSK EAY
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : AK4 adenylate kinase 4 [ Homo sapiens ]
Synonyms : AK3L1; adenylate kinase 3-like 1; AK3L1 adenylate kinase 3-like 1; AK3; AK4; MGC166959; EC 2.7.4.3; OTTHUMP00000010594; ATP-AMP transphosphorylase; GTP:AMP phosphotransferase; Adenylate kinase 3-like; adenylate kinase 3; mitochondrial adenylate kinase-3; nucleoside-triphosphate-adenylate kinase
Gene ID : 205
mRNA Refseq : NM_001005353
Protein Refseq : NP_001005353
MIM : 103030
UniProt ID : P27144
Chromosome Location : 1p31.3
Pathway : Purine metabolism
Function : ATP binding; GTP binding; adenylate kinase activity; nucleotide binding; transferase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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