|Official Full Name||A kinase (PRKA) anchor protein (yotiao) 9|
|Background||The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3.|
|Synonyms||AKAP9; A kinase (PRKA) anchor protein (yotiao) 9; A-kinase anchor protein 9; A kinase anchor protein; 350kDa; A kinase anchoring protein 450; AKAP9 BRAF fusion protein; AKAP120 like protein; AKAP350; AKAP450; centrosome and golgi localized protein; CG NAP; HYPERION; KIAA0803; kinase N associated protein; MU RMS 40.16A; PPP1R45; PRKA9; protein kinase A anchoring protein 9; protein phosphatase 1; regulatory subunit 45; YOTIAO; protein yotiao; protein hyperion; AKAP 120-like protein; AKAP9-BRAF fusion protein; kinase N-associated protein; A-kinase anchor protein 350 kDa; A-kinase anchor protein 450 kDa; protein phosphatase 1, regulatory subunit 45; centrosome- and Golgi-localized PKN-associated protein; AKAP-9; CG-NAP; MU-RMS-40.16A|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
akap9 involved in several pathways and played different roles in them. We selected most pathways akap9 participated on our site, such as ARMS-mediated activation, Activation of NMDA receptor upon glutamate binding and postsynaptic events, Anchoring of the basal body to the plasma membrane, which may be useful for your reference. Also, other proteins which involved in the same pathway with akap9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|ARMS-mediated activation||CSF2RB; CSF2RA; SPRED3; PEA15A; DUSP1; CSF2; NEFLB; RASGRP4; NRG2A; DUSP4|
|Activation of NMDA receptor upon glutamate binding and postsynaptic events||CREB1; DLG4; ADCY8; ADCY1; CAMKK1B; CREB1B; NEFLB; SLC14A2; PDPK1A; ADCY3|
|Anchoring of the basal body to the plasma membrane||CEP78; CEP290; SSNA1; CLASP1; MARK4; DCTN2; TUBG1; ODF2B; FBF1; AKAP9|
|Assembly of the primary cilium||DYNLL2A; CKAP5; RABL5; CEP89; HSPB11; CNGA2; LZTFL1; TNPO1; CC2D2A; TMEM67|
|Axon guidance||ARHGEF28; SHB; ARPC2; MAPK3; DCX; EFNB3; SLIT2; PPP3CC; RHOA; GNAI1|
|CREB phosphorylation through the activation of CaMKII||SLC14A2; NETO2; DLG4; NEFLB; CREB1B; AKAP9|
|CREB phosphorylation through the activation of Ras||NEFLB; DLG4; SLC14A2; PDPK1A; AKAP9|
|Cell Cycle||KIF18A; TP53BP1; MCM2; E2F5; ERCC6L; MCPH1; SMAD3; SYCP2; CEP57; RAD21B|
akap9 has several biochemical functions, for example, ion channel binding, potassium channel regulator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by akap9 itself. We selected most functions akap9 had, and list some proteins which have the same functions with akap9. You can find most of the proteins on our site.
|ion channel binding||KCNB2; KCNE1L; PKD1; LRRK2; ACTN2; KCNIP2; EPN1; SRC; TRAPPC2; KCNC1|
|potassium channel regulator activity||KCNV1; LRRC26; KCNE3; KCNAB2; AKAP9; KCNIP1; ARPP19A; KCNMB3; KCNIP2; SGK1|
|protein binding||ANG; TOR1A; FAM50B; VPS16; EPM2AIP1; KRR1; MMP2; ACTA1; NDFIP1; XRN1|
|protein complex scaffold||ARRB2; CHCHD3; SLC9A1; DISC1; AKAP9; SLC9A3R2; MAGI3; DLG1; MAGI1; WWC3|
|protein kinase A regulatory subunit binding||C2orf88; AKAP7; RYR2; AKAP1; PJA2; AKAP8; EZR; AKAP6; KCNQ1; ARFGEF2|
|receptor binding||WNT7AA; WNT2BA; HNF4A; PARK7; RSPO3; UFD1L; HSD17B4; NXPH1; SMARCD1; IL29|
akap9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with akap9 here. Most of them are supplied by our site. Hope this information will be useful for your research of akap9.
GOLGA2; KDM1A; p29991-pro_0000037946; ORF; PSTPIP1; ELF3; SMYD2; ACTR3B; PUF60; TULP3; TDP2; C1orf94; pbuO; q81mm5_bacan; ybgA