|Official Full Name||aldehyde dehydrogenase 1 family, member L1|
|Background||The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.|
|Synonyms||ALDH1L1; aldehyde dehydrogenase 1 family, member L1; formyltetrahydrofolate dehydrogenase , FTHFD; cytosolic 10-formyltetrahydrofolate dehydrogenase; 10 fTHF; cytosolic 10 formyltetrahydrofolate dehydrogenase; 10-FTHFDH; formyltetrahydrofolate dehydrogena|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
aldh1l1 involved in several pathways and played different roles in them. We selected most pathways aldh1l1 participated on our site, such as Folate-Alcohol and Cancer Pathway, One Carbon Metabolism, One carbon pool by folate, which may be useful for your reference. Also, other proteins which involved in the same pathway with aldh1l1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Folate-Alcohol and Cancer Pathway||CYP2E1; ALDH1L1|
|One Carbon Metabolism||FTCD; AHCY; MTFMT; MTHFD2; MTHFS; ST20-MTHFS; ALDH1L1|
|One carbon pool by folate||MTHFR; MTHFD1B; SHMT2; MTHFS; MTFMT; ALDH1L1; FTCD; ALDH1L2; TYMS; MTR|
|folate transformations I||ALDH1L1; MTHFD2; ALDH1L2; MTHFSD|
aldh1l1 has several biochemical functions, for example, aldehyde dehydrogenase (NAD) activity, catalytic activity, formyltetrahydrofolate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by aldh1l1 itself. We selected most functions aldh1l1 had, and list some proteins which have the same functions with aldh1l1. You can find most of the proteins on our site.
|aldehyde dehydrogenase (NAD) activity||ALDH6A1; ALDH3B2; Aldh1a7; ALDH3A1; ALDH3A2B; ALDH9A1; ALDH1L2; ALDH4A1; ALDH1A3; ALDH1A1|
|catalytic activity||ALDOCA; HHIPL1; HSD17B1; PARP3; TM9SF1; PFKFB2A; GTF2F1; ISOC2; GOT1L1; ACSL3A|
|formyltetrahydrofolate dehydrogenase activity||ALDH1L2; ALDH1L1|
|hydroxymethyl-, formyl- and related transferase activity||ALDH1L1; ALDH1L2|
|methyltransferase activity||SUV39H1A; FAM86C; PRMT8B; CMTR2; PRDM15; METTL17; MLL1; FTSJD1; COMTB; SETDB1B|
aldh1l1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with aldh1l1 here. Most of them are supplied by our site. Hope this information will be useful for your research of aldh1l1.