alox12

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alox12

Official Full Name arachidonate 12-lipoxygenase
Background Arachidonate 12-lipoxygenase, 12S-type is an enzyme that in humans is encoded by the ALOX12 gene.
Synonyms ALOX12; arachidonate 12-lipoxygenase; arachidonate 12-lipoxygenase, 12S-type; 12S-type; 12 Lox; 12(S) lipoxygenase; 12S LOX; 12S-lipoxygenase; 12S-LOX; Alox 12; Alox12L; Alox15; Arachidonate 12 lipoxygenase 12S type; Arachidonate 12 lipoxygenase; Arachidonate 12 lipoxygenase leukocyte type; Arachidonate 12 lipoxygenase, 12S type; Arachidonate 12 lipoxygenase, leukocyte type; EC1.13.11.31; LOG 12; LOG12; LOX12_HUMAN; Platelet type 12 lipoxygenase; Platelet type lipoxygenase 12; Platelet-type lipoxygenase 12; P-12LO; Alox12p; 9930022G08Rik
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293T
    • Insect cell
    • Insect Cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Alox12-104M Recombinant Mouse Alox12 Protein, His-tagged Insect cell His
    Human ALOX12-01H Recombinant human ALOX12, His-tagged E.coli His
    Human ALOX12-2031H Recombinant Human ALOX12 protein, His & T7-tagged E.coli His/T7
    Human ALOX12-2197H Recombinant Human ALOX12 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ALOX12-26002TH Recombinant Human ALOX12 Wheat Germ N/A
    Human ALOX12-269H Recombinant Human ALOX12 Mammalian Cell His
    Human ALOX12-482H Recombinant Human ALOX12 Protein, GST-tagged Wheat Germ GST
    Human ALOX12-64HCL Recombinant Human ALOX12 cell lysate N/A
    Mouse Alox12-021M Recombinant mouse Alox12 Protein, His-tagged Insect Cells His
    Mouse Alox12-578M Recombinant Mouse Alox12 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Alox12-584M Recombinant Mouse Arachidonate 12-lipoxygenase, His-tagged Insect Cell His
    Zebrafish ALOX12-10019Z Recombinant Zebrafish ALOX12 Mammalian Cell His

    alox12 involved in several pathways and played different roles in them. We selected most pathways alox12 participated on our site, such as Arachidonic acid metabolism, Metabolic pathways, Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with alox12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism GGTLC1; FAAH2; PTGESL; PLA2G10; PTGDS; CYP2C70; GGT1; HPGDS; GPX5; PTGS2
    Metabolic pathways PPAP2A; ALDH1A2; SHMT1; ALOX12B; AANAT2; AMPD2; CYP27A1; NT5C1A; PAFAH2; PPAP2D
    Serotonergic synapse HTR1E; MAP2K1; HTR3A; HTR2B; ALOX15; GNG11; BRAF; KCND2; HTR2A; PTGS2
    Inflammatory mediator regulation of TRP channels PRKCA; PLA2G4F; MAPK13; CYP2C39; TRPV1; CALM4; TRPV3; PRKCG; PIK3CD; CYP4A10

    alox12 has several biochemical functions, for example, arachidonate 12-lipoxygenase activity, hepoxilin A3 synthase activity, hepoxilin-epoxide hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by alox12 itself. We selected most functions alox12 had, and list some proteins which have the same functions with alox12. You can find most of the proteins on our site.

    Function Related Protein
    arachidonate 12-lipoxygenase activity ALOX12E; ALOX12B; ALOX15; ALOX12
    hepoxilin A3 synthase activity ALOX15; ALOX12
    hepoxilin-epoxide hydrolase activity ALOX12; ALOX15
    iron ion binding NOS2; CYP2J6; CYP2AD3; NDOR1; CYP24A1; CYP26A1; PHF8; CYP2Y3; CYP2R1; CYP2D26
    linoleate 13S-lipoxygenase activity ALOX15B; ALOX12; ALOX8
    oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ADOA; P4HA1B; ALOX5B.2; TMLHE; P4HA1A; P4HA1; ALOX12B; ALOX8; P4HA2; ADOB
    protein binding DDX42; MCRS1; REST; C12orf43; SMN1; NRSN1; KLC1; NLRC5; KDM1A; NOS1AP

    alox12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with alox12 here. Most of them are supplied by our site. Hope this information will be useful for your research of alox12.

    KRT5; LMNA; PLA2G2A; ITGB4; TRIB1

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