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Official Full Name ALX homeobox 3
Background This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this genes promoter is associated with advanced-stage neuroblastoma tumors.
Synonyms ALX3; ALX homeobox 3; aristaless like homeobox 3; homeobox protein aristaless-like 3; ALX 3; Homeobox protein aristaless like 3; MGC138212; MGC141988; Proline rich transcription factor ALX3; OTTHUMP00000013372; aristaless-like homeobox 3; proline-rich transcription factor ALX3; FND1
    • Species :
    • Human
    • Mouse
    • Source :
    • E. coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALX3-1368H Recombinant Human ALX3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ALX3-1991H Recombinant Human ALX3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ALX3-510H Recombinant Human ALX3 protein, GST-tagged Wheat Germ GST
    Human ALX3-511H Recombinant Human ALX3 protein, GST-tagged E. coli GST
    Mouse ALX3-1582M Recombinant Mouse ALX3 Protein Mammalian Cell His
    Mouse Alx3-589M Recombinant Mouse Alx3 Protein, MYC/DDK-tagged HEK293T MYC/DDK

    ALX3 involved in several pathways and played different roles in them. We selected most pathways ALX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    ALX3 has several biochemical functions, for example, DNA binding, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALX3 itself. We selected most functions ALX3 had, and list some proteins which have the same functions with ALX3. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding TIGD5; ZNF2; EP400; ZFP37; DNTTIP1; ZNF529; DR1; ZNF74; ZNF784; PHC2B
    sequence-specific DNA binding Ar; ATF7A; NR2C2; HOXC1A; AHR2; LHX6; CENPB; NOTCH1; TCF7L1B; ATF5A
    transcription factor activity, sequence-specific DNA binding KLF11; KAT7; FOXE1; TEF; SP140; ZNF323; FLI1B; RXRAB; SCAND3; BTBD8

    ALX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALX3.

    Fernandez-Perez, A; Vallejo, M; et al. Pdx1 and USF transcription factors co-ordinately regulate Alx3 gene expression in pancreatic beta-cells. BIOCHEMICAL JOURNAL 463:287-296(2014).
    Liu, WB; Han, F; et al. Epigenetic silencing of Aristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer. INTERNATIONAL JOURNAL OF CANCER 134:1311-1322(2014).

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