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AMN

  • Official Full Name

    amnionless homolog (mouse)

  • Overview

    The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila.
  • Synonyms

    AMN; amnionless homolog (mouse); protein amnionless; visceral endoderm-specific type 1 transmembrane protein; PRO1028;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AMN-777H Active Recombinant Human AMN Protein, His-tagged Mammalian cells His Val20-Ala358
Human AMN-768H Recombinant Human AMN Mammalian Cell His
Human AMN-7084H Recombinant Human AMN, His-tagged E.coli His 20-357aa
Human AMN-1987H Recombinant Human AMN Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human AMN-2462H-B Recombinant Human AMN Protein Pre-coupled Magnetic Beads HEK293
Human AMN-2462H Recombinant Human AMN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Amn-1612M Recombinant Mouse Amn Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Amn-136R Recombinant Rat Amn Protein, His-tagged E.coli N-His Ala20-Glu268
Chicken AMN-4907C Recombinant Chicken AMN Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AMN Related Articles
  • AMN Related Research Area

AMN involved in several pathways and played different roles in them. We selected most pathways AMN participated on our site, such as Cobalamin (Cbl, vitamin B12) transport and metabolism, Defective AMN causes hereditary megaloblastic anemia 1, Defective CUBN causes hereditary megaloblastic anemia 1, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cobalamin (Cbl, vitamin B12) transport and metabolismELA2L;MMADHC;LOC100686744;TCN1;AMN;CTRC;CD320;CBLC-1;ELA2
Defective AMN causes hereditary megaloblastic anemia 1
Defective CUBN causes hereditary megaloblastic anemia 1
Defects in cobalamin (B12) metabolismAMN;MTRR;MMADHC;MMAA
Defects in vitamin and cofactor metabolismAMN;MMAA;MTRR;MMADHC
DiseaseJAG2;PSIP1;NUP35;PSTPIP2;RNF43;OS9;DERL2;CHMP4B;gag
Diseases of metabolismGYG1;MTRR;MMAA;MMADHC;SFTPC;EPM2A;CYP11A1;GYG2;CCDC59
HDL-mediated lipid transportCETP;BMP1A;Alb;APOA1B;APOC2;ABCA1;AMN

AMN has several biochemical functions, for example, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMN itself. We selected most functions AMN had, and list some proteins which have the same functions with AMN. You can find most of the proteins on our site.

Function Related Protein
receptor bindingINHA;NPFF;PLAUR;BMP3;TMED1;FGF10B;NPPC;SRPX2;FRK

AMN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMN here. Most of them are supplied by our site. Hope this information will be useful for your research of AMN.

Storm, T; Zeitz, C; et al. Detailed investigations of proximal tubular function in Imerslund-Grasbeck syndrome. BMC MEDICAL GENETICS 14:-(2013).
Christensen, EI; Nielsen, R; et al. From bowel to kidneys: the role of cubilin in physiology and disease. NEPHROLOGY DIALYSIS TRANSPLANTATION 28:274-281(2013).
  • Q&As
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