ANXA2R

  • Official Full Name

    annexin A2 receptor

  • Synonyms

    AX2R; AXIIR; C5orf39;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ANXA2R-380H Recombinant Human ANXA2R Protein, GST-His-tagged E.coli GST/His
Human ANXA2R-632H Recombinant Human ANXA2R protein, GST-tagged Wheat Germ GST
Human ANXA2R-8010HCL Recombinant Human C5orf39 293 Cell Lysate HEK293 N/A
Human ANXA2R-1315HF Recombinant Full Length Human ANXA2R Protein, GST-tagged In Vitro Cell Free System GST
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ANXA2R Related Articles

ANXA2R involved in several pathways and played different roles in them. We selected most pathways ANXA2R participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA2R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ANXA2R has several biochemical functions, for example, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA2R itself. We selected most functions ANXA2R had, and list some proteins which have the same functions with ANXA2R. You can find most of the proteins on our site.

Function Related Protein
receptor activityMED12;CADM1B;ABP1;SV2A;CNTNAP1;MED30;NLGN4B;VMN1R44;NOTCH1B

ANXA2R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA2R here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA2R.

Canas, F; Simonin, L; et al. Annexin A2 autoantibodies in thrombosis and autoimmune diseases. THROMBOSIS RESEARCH 135:226-230(2015).
Mei, M; Ye, JQ; et al. Identification of novel viral receptors with cell line expressing viral receptor-binding protein. SCIENTIFIC REPORTS 5:-(2015).
  • Q&As
  • Reviews

Q&As (10)

Ask a question
Are there any diseases associated with ANXA2R? 04/07/2021

ANXA2R has been implicated in cancer progression and metastasis. It is highly expressed in several cancer types, and its overexpression has been associated with poor prognosis. ANXA2R has also been suggested to play a role in autoimmune diseases and pathogen infection, although more research is needed to establish these associations.

Are there any therapeutic implications for targeting ANXA2R? 11/22/2020

Targeting ANXA2R has shown potential for therapeutic purposes. In cancer, blocking ANXA2R or its interaction with Annexin A2 may inhibit tumor invasion and metastasis. This could be achieved through the development of small molecule inhibitors, antibodies, or peptides that disrupt ANXA2R function. Additionally, modulating ANXA2R activity might be useful in cardiovascular diseases and autoimmune disorders, although more research is needed to identify specific therapeutic strategies.

Can ANXA2R interact with other proteins? 08/21/2020

Yes, ANXA2R can interact with a variety of proteins. One of its well-known interactions is with Annexin A2, forming a receptor-ligand complex. It can also interact with other cell adhesion molecules, signaling proteins, and cytoskeletal proteins, contributing to its diverse functions.

Can ANXA2R be used as a diagnostic or prognostic marker? 07/28/2020

ANXA2R has shown promise as a diagnostic and prognostic marker in certain cancers. Its overexpression has been associated with poor prognosis in breast cancer, colorectal cancer, and ovarian cancer. However, further studies are needed to validate its utility as a clinical marker in different diseases.

How is ANXA2R expressed in different tissues? 05/15/2020

ANXA2R is expressed in various tissues and cell types. It has been detected in the endothelium, epithelium, smooth muscle cells, and neurons. Its expression levels can vary depending on the tissue type and physiological context.

How is ANXA2R implicated in cancer? 05/03/2020

ANXA2R has been implicated in cancer through its involvement in processes such as cell migration, invasion, and metastasis. Its overexpression has been observed in various types of cancer and is often associated with poor prognosis. ANXA2R can promote tumor cell invasion by interacting with Annexin A2 and other proteins involved in cell adhesion and cytoskeletal rearrangement. Furthermore, ANXA2R can modulate signaling pathways that contribute to tumor growth and survival.

Are there any ongoing research studies related to ANXA2R? 12/10/2019

Yes, there are ongoing research studies investigating various aspects of ANXA2R. Some studies aim to elucidate the precise role of ANXA2R in cancer progression, as well as its potential as a therapeutic target. Other studies focus on understanding ANXA2R's involvement in cardiovascular diseases, autoimmune disorders, and other pathological conditions. Additionally, continuing research aims to identify novel molecular mechanisms and signaling pathways associated with ANXA2R.

How is ANXA2R related to Annexin A2? 12/02/2019

ANXA2R is the receptor for Annexin A2. Annexin A2 is a calcium-dependent phospholipid-binding protein that interacts with ANXA2R to form a receptor-ligand complex. This complex is involved in various cellular functions, including the regulation of cell adhesion and membrane trafficking.

How is ANXA2R regulated? 05/10/2018

ANXA2R expression and activity can be regulated at multiple levels. Transcriptional regulation by various transcription factors can influence ANXA2R expression. Post-translational modifications, such as phosphorylation and glycosylation, can modulate its function and localization. Furthermore, signaling pathways, growth factors, and cytokines can regulate ANXA2R activity, affecting its interactions with other proteins and downstream signaling events.

Is ANXA2R involved in any other diseases or conditions? 07/20/2017

Apart from cancer, ANXA2R has been implicated in several other diseases and conditions. It has been associated with cardiovascular diseases, such as atherosclerosis and cardiac fibrosis, playing a role in vascular remodeling, endothelial dysfunction, and inflammation. ANXA2R has also been linked to autoimmune disorders like rheumatoid arthritis and systemic lupus erythematosus, potentially contributing to immune dysregulation and tissue damage.

Customer Reviews (4)

Write a review
Reviews
05/30/2021

    Highly recommended and known for its outstanding performance in ELISA, the ANXA2R protein is a top choice for researchers in protein electron microscopy structure analysis.

    02/09/2021

      Its versatility and reliability make it a great asset in the pursuit of scientific discoveries.

      05/22/2018

        Its exceptional properties and reliable results make it a valuable tool in various experimental applications.

        07/12/2017

          With the ANXA2R protein, researchers can confidently delve into the complexity of protein structures and gain deeper insights into their functions.

          Ask a Question for All ANXA2R Products

          Required fields are marked with *

          My Review for All ANXA2R Products

          Required fields are marked with *

          logo

          FOLLOW US

          Terms and Conditions        Privacy Policy

          Copyright © 2024 Creative BioMart. All Rights Reserved.

          Contact Us

          • /

          Stay Updated on the Latest Bioscience Trends