|Official Full Name||amine oxidase, copper containing 2 (retina-specific)|
|Background||Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.|
|Synonyms||AOC2; amine oxidase, copper containing 2 (retina-specific); retina-specific copper amine oxidase; DAO2; RAO; Amine oxidase [copper containing]; Amine oxidase copper containing 2 (retina specific); Amine oxidase copper containing 2; Retina specific copper amine oxidase; SSAO; semicarbazide-sensitive amine oxidase|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
aoc2 involved in several pathways and played different roles in them. We selected most pathways aoc2 participated on our site, such as Glycine, serine and threonine metabolism, Tyrosine metabolism, Phenylalanine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with aoc2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Glycine, serine and threonine metabolism||MAOA; SRR; AGXT2; PHGDH; CHDH; PSAT1; THA1; DAO; AGXTB; ALAS1|
|Tyrosine metabolism||AOX2P; TH; TPO; HPDB; MIF; FAH; COMTA; ALDH3B2; HGD; AOX3L1|
|Phenylalanine metabolism||MAOA; TAT; IL4I1; GM4952; ALDH3B2; GOT2B; MIF; HPDA; GOT2; HPDB|
|beta-Alanine metabolism||MLYCD; ALDH7A1; SRM; ALDH3A1; ALDH3A2; ALDH1A3; ALDH3B2; ALDH2; HADHAB; ALDH9A1B|
|Metabolic pathways||TGDS; CYP27B1; MGAT3A; GALCA; Acsm2a; PI4KB; CEPT1; CYP26B1; CERS5; EXT1A|
aoc2 has several biochemical functions, for example, aliphatic-amine oxidase activity, aminoacetone:oxygen oxidoreductase(deaminating) activity, copper ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by aoc2 itself. We selected most functions aoc2 had, and list some proteins which have the same functions with aoc2. You can find most of the proteins on our site.
|aliphatic-amine oxidase activity||AOC3; AOC2|
|aminoacetone:oxygen oxidoreductase(deaminating) activity||AOC3; AOC2|
|copper ion binding||CCC2; PAM; MT3; LOXL4; DBH; TP53; MT1; LOXL1; SOD1; AOC3|
|electron carrier activity||UGDH; CYCSB; AOX1; ASPH; ALDH4A1; PHGDH; MAOB; GLRX; AKR1A1; COX7A2A|
|phenethylamine:oxygen oxidoreductase (deaminating) activity||AOC3; AOC2|
|primary amine oxidase activity||VCAM1; AOC3; AOC2; MAOA; MAOB; ABP1; AOC1|
|quinone binding||ABP1; VKORC1L1; SQRDL; AMOTL1; VKORC1; NDUFS2; HHIPL1; TP53I3; AOC3; ETFDH|
|tryptamine:oxygen oxidoreductase (deaminating) activity||AOC2; AOC3|
aoc2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with aoc2 here. Most of them are supplied by our site. Hope this information will be useful for your research of aoc2.