| Description : |
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
83.5 kDa |
| AA Sequence : |
MHLKIVLAFLALSLITIFALAYVLL TSPGGSSQPPHCPSVSHRAQPWPHP GQSQLFADLSREELTAVMRFLTQRL GPGLVDAAQAQPSDNCIFSVELQLP PKAAALAHLDRGSPPPAREALAIVL FGGQPQPNVSELVVGPLPHPSYMRD VTVERHGGPLPYHRRPVLRAEFTQM WRHLKEVELPKAPIFLSSTFNYNGS TLAAVHATPRGLRSGDRATWMALYH NISGVGLFLHPVGLELLLDHRALDP AHWTVQQVFYLGHYYADLGQLEREF KSGRLEVVRVPLPPPNGASSLRSRN SPGPLPPLQFSPQGSQYSVQGNLVV SSLWSFTFGHGVFSGLRIFDVRFQG ERIAYEVSVQECVSIYGADSPKTML TRYLDSSFGLGRNSRGLVRGVDCPY QATMVDIHILVGKGAVQLLPGAVCV FEEAQGLPLRRHHNYLQNHFYGGLA SSALVVRSVSSVGNYDYIWDFVLYP NGALEGRVHATGYINTAFLKGGEEG LLFGNRVGERVLGTVHTHAFHFKLD LDVAGLKNWVVAEDVVFKPVAAPWN PEHWLQRPQLTRQVLGKEDLTAFSL GSPLPRYLYLASNQTNAWGHQRGYR IQIHSPLGIHIPLESDMERALSWGR YQLVVTQRKEEESQSSSIYHQNDIW TPTVTFADFINNETLLGEDLVAWVT ASFLHIPHAEDIPNTVTLGNRVGFL LRPYNFFDEDPSIFSPGSVYFEKGQ DAGLCSINPVACLPDLAACVPDLPP FSYHGFTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
