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Official Full Name aquaporin 6, kidney specific
Background The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13.
Synonyms AQP6; aquaporin 6, kidney specific; AQP2L; aquaporin-6; hKID; AQP-6; kidney-specific aquaporin; aquaporin-6, kidney specific; aquaporin 2-like, kidney specific; KID
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AQP6-8766HCL Recombinant Human AQP6 293 Cell Lysate HEK293 N/A
    Mouse AQP6-1825M Recombinant Mouse AQP6 Protein Mammalian Cell His
    Rat AQP6-740R Recombinant Rat AQP6 Protein Mammalian Cell His

    aqp6 involved in several pathways and played different roles in them. We selected most pathways aqp6 participated on our site, such as Aquaporin-mediated transport, Passive transport by Aquaporins, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with aqp6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Aquaporin-mediated transport GNB3A; MIP; PRKAR1AA; AQP10B; ADCY6; AQP3A; AQP11; GNB5; MIPA; AQP3B
    Passive transport by Aquaporins AQP10; AQP3B; MIPA; AQP8A.1; AQP9B; AQP1A.1; AQP3A; AQP1A.2; MIP; AQP10B
    Transmembrane transport of small molecules SLC43A1A; TTYH1; LCN1; SLC17A1; SLC7A3; SLC4A3; SLC26A6L; SLC30A5; MIPB; SLC30A1B

    aqp6 has several biochemical functions, for example, anion channel activity, glycerol channel activity, nitrate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by aqp6 itself. We selected most functions aqp6 had, and list some proteins which have the same functions with aqp6. You can find most of the proteins on our site.

    Function Related Protein
    anion channel activity CCT8L2; AQP6
    glycerol channel activity AQP7; MIPA; AQP8; AQP9B; AQP4; AQP1; AQP9; AQP3; AQP8A.1; AQP6
    nitrate transmembrane transporter activity AQP6
    water channel activity AQP7; AQP10B; AQP6; AQP8A.1; AQP4; AQP10A; AQP8; AQP3; AQP9B; MIP

    aqp6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with aqp6 here. Most of them are supplied by our site. Hope this information will be useful for your research of aqp6.

    Ishiyama, G; Lopez, IA; et al. Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere's disease and acoustic neuroma. CELL AND TISSUE RESEARCH 340:407-419(2010).
    Matsuki-Fukushima, M; Hashimoto, S; et al. Presence and localization of aquaporin-6 in rat parotid acinar cells. CELL AND TISSUE RESEARCH 332:73-80(2008).

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